Results 91 to 100 of about 693,652 (267)

Metric Dimension in fuzzy(neutrosophic) Graphs-VI [PDF]

open access: yes, 2021
New notion of dimension as set, as two optimal numbers including metric number, dimension number and as optimal set are introduced in individual framework and in formation of family. Behaviors of twin and antipodal are explored in fuzzy(neutrosophic) graphs. Fuzzy(neutrosophic) graphs, under conditions, fixed-edges, fixed-vertex and strong fixed-vertex
openaire   +6 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Vertex and edge resolvability of some drug structures

open access: yesResults in Chemistry
Distance-based parameters are crucial in studying drug structures as they help in uniquely identifying and characterizing the molecular structure through the analysis of graph representations, thereby aiding in the understanding of molecular properties ...
Ayesha Andalib Kiran   +3 more
doaj   +1 more source

DIMENSI METRIK PADA GRAF Rn(q; r)m

open access: yesJurnal Matematika UNAND, 2019
The metric dimension of a connected graph G is the cardinality of minimum resolving set in graph G. In this research, how to find the metric dimension of Rn(q; r)m graph. Rn(q; r)m graph is constructing by subdivision operation on Lobster graph Ln(q; r).
Rendy Aditya Pratama   +2 more
doaj   +1 more source

Metric dimension of dual polar graphs

open access: yes, 2017
A resolving set for a graph $\Gamma$ is a collection of vertices $S$, chosen so that for each vertex $v$, the list of distances from $v$ to the members of $S$ uniquely specifies $v$.
Bailey, Robert F., Spiga, Pablo
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Metric dimension and equivalent metrics [PDF]

open access: yesFundamenta Mathematicae, 1968
Roberts, J. H., Slaughter, F. G. jun.
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Resolvability in Hypergraphs

open access: yes, 2018
This article emphasizes an extension of the study of metric and par- tition dimension to hypergraphs. We give a sharp lower bounds for the metric and partition dimension of hypergraphs in general and give exact values under specified conditions.eral and ...
Haider, Azeem   +3 more
core  

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