Results 81 to 90 of about 669,922 (254)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Metric dimension of dual polar graphs
, 2017 A resolving set for a graph $\Gamma$ is a collection of vertices $S$, chosen so that for each vertex $v$, the list of distances from $v$ to the members of $S$ uniquely specifies $v$.
Bailey, Robert F., Spiga, Pablo
core
Slant and Legendre null curves in 3-dimensional Sasaki-like almost contact B-metric manifolds [PDF]
, 2021 Galia Nakova, Simeon Zamkovoy
openalex +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Metric Basis of Four-Dimensional Klein Bottle [PDF]
, 2023 Ali N. A. Koam +4 more
openalex +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
The metric dimension of circulant graphs [PDF]
Opuscula MathematicaA pair of vertices \(x\) and \(y\) in a graph \(G\) are said to be resolved by a vertex \(w\) if the distance from \(x\) to \(w\) is not equal to the distance from \(y\) to \(w\).
Tapendra BC, Shonda Dueck
doaj +1 more source
, 2018 This article emphasizes an extension of the study of metric and par- tition dimension to hypergraphs. We give a sharp lower bounds for the metric and partition dimension of hypergraphs in general and give exact values under specified conditions.eral and ...
Haider, Azeem +3 more
core
Three-Dimensional Investigation of the Metric Properties of Parabolic Double Projection Involving Catadioptric Camera [PDF]
, 2022 Ahmed Hamdy, Ahmed Elsherif, Saiid Shebl
openalex +1 more source