Results 81 to 90 of about 654,066 (314)
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
A Central Local Metric Dimension of Generalized Fan Graph, Generalized Broken Fan Graph, and Cm ⊙ K¯m [PDF]
The central local metric dimension is a new variation of local metric dimension that introduced in 2023. The central local metric dimension is a new concept that enriches research studies in graph theory, especially in the field of metric dimension. This
Listiana Yuni, Susilowati Liliek, Slamin
doaj +1 more source
Fractional metric dimension of metal-organic frameworks
Metal-organic frameworks (MOF(n)) are organic-inorganic hybrid crystalline porous materials that consist of a regular array of positively charged metal ions surrounded by organic ‘linker’ molecules.
Raza Mohsin+2 more
doaj +1 more source
Optimal Fault-Tolerant Resolving Set of Power Paths
In a simple connected undirected graph G, an ordered set R of vertices is called a resolving set if for every pair of distinct vertices u and v, there is a vertex w∈R such that d(u,w)≠d(v,w).
Laxman Saha+4 more
doaj +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Metric Mean Dimension and Mean Hausdorff Dimension Varying the Metric
AbstractLet $$f:\mathbb {M}\rightarrow \mathbb {M}$$ f : M → M be a continuous map on a compact metric space $$\mathbb {M}$$ M equipped with a fixed metric d, and ...
Muentes Acevedo, Jeovanny de Jesus+3 more
openaire +3 more sources
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
The Metric Dimension of Amalgamation of Cycles [PDF]
For an ordered set W = {w_1, w_2 , ..., w_k } of vertices and a vertex v in a connected graph G, the representation of v with respect to W is the ordered k-tuple r(v|W) = (d(v,w_1), d(v,w_2 ), ..., d (v,w_k )), where d(x,y) represents the distance ...
Baskoro, Edy Tri+3 more
core
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source