Results 111 to 120 of about 282,648 (277)

Entanglement entropy, horizons and holography

open access: yesPhysics Letters B, 2019
We study the entanglement entropy in spaces with horizons, such as Rindler or de Sitter space, using holography. We employ appropriate parametrizations of AdS space in order to obtain a Rindler or static de Sitter boundary metric.
D. Giataganas, N. Tetradis
doaj   +1 more source

On finsler entropy of smooth distributions and Stefan-Sussman foliations

open access: yes, 2015
Using the definition of entropy of a family of increasing distances on a compact metric set given in [10] we introduce a notion of Finsler entropy for smooth distributions and Stefan-Sussmann foliations.
Pelletier, F.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Quantifying Three-Dimensional Street Network Orientation Entropy in Chongqing, China: Implications for Urban Spatial Order and Environmental Perception

open access: yesBuildings
Orientation entropy serves as a critical metric for assessing the directional disorder of urban street networks. However, conventional two-dimensional (2D) approaches neglect vertical variations, limiting their applicability in cities with complex ...
Hao Rao, Leyao Chen, Cui Liu
doaj   +1 more source

Complexity Regularization and Local Metric Entropy

open access: yes, 2014
In the context of Structural Risk Minimization, one is presented a sequence of classes $\{\mathcal{G}_j\}$ from which, given a random sample $(X_i,Y_i)$ one wants to choose a strongly consistent estimator. For certain types of classes of functions, we present a criterion to choose an estimator, based on the minimization of the sum of empirical error ...
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

ENTROPY RIGIDITY FOR METRIC SPACES

open access: yesThe Pure and Applied Mathematics, 2012
This is a survey on the volume entropy and its rigidity of various metric spaces. This survey is aimed to summarize recent results as well as remaining open questions and possible directions on this subject.
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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