Results 101 to 110 of about 1,013,760 (323)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
On the extremal semi-Lipschitz functions
Journal of Numerical Analysis and Approximation Theory, 2002 The extremal elements of the unit balls of Banach spaces play an important role in the study of the geometry of the space as well as in various applications.
Costică Mustăţa
doaj +2 more sources
Mobile Stroke Unit Operational Metrics: Institutional Experience, Systematic Review and Meta-Analysis [PDF]
, 2022 Nathaniel R. Ellens +13 more
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NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
MathematicsDefining an adequate unit size is often crucial in brain imaging analysis, where datasets are complex, high-dimensional, and computationally demanding. Unit size refers to the spatial resolution at which brain data is aggregated for analysis.
Jihnhee Yu, HyunAh Lee, Zohi Sternberg
doaj +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
On the boundary behavior of the holomorphic sectional curvature of the Bergman metric
Le Matematiche, 2006 We obtain a conceptually new differential geometric proof of P. F. Klembeck’s result (cf. [9]) that the holomorphic sectional curvature k g (z ) of the Bergman metric of a strictly pseudoconvex domain Ω ⊂ ℂ n approaches −4/(n + 1 ...
Elisabetta Barletta
doaj
A Patient Flow Analysis: Identification of Process Inefficiencies and Workflow Metrics at an Ambulatory Endoscopy Unit [PDF]
, 2016 Rowena Almeida +3 more
openalex +1 more source