Results 111 to 120 of about 5,311,035 (359)
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
REMATThis study aims to analyze parabolas in the two dimensional unit disk equipped with a Funk metric. The analysis leads to four types of parabolas are obtained, due to the non-reversibility of the Funk metric.
Newton Mayer Solórzano Chávez +2 more
doaj +1 more source
On the integrability of the isotropic almost complex structures and harmonic unit vector fields [PDF]
arXiv, 2016 Aguilar introduced isotropic almost complex structures $J_{\delta , \sigma}$ on the tangent bundle of a Riemannian manifold $(M, g)$. In this paper, some results will be obtained on the integrability of these structures. These structures with the Liouville 1-form define a class of Riemannian metrics $g_{\delta , \sigma}$ on $T M$ which are a ...
arxiv
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Visualizing the Unit Ball for the Teichmüller Metric [PDF]
Experimental Mathematics, 2016 We describe a method to compute the norm on the cotangent space to the moduli space of Riemann surfaces associated to the Finsler Teichm ller metric. Our method involves computing the periods of abelian double covers and is easy to implement for Riemann surfaces presented as algebraic curves using existing tools for approximating period matrices of ...
openaire +3 more sources
Metrics On The Quantum Heisenberg Manifold [PDF]
arXiv, 2001 Compact quantum metric spaces are order unit spaces along with a Lip norm. On the order unit space of the selfadjoint elements of the dense subalgebra of smooth elements in the quantum Heisenberg manifold we construct Lip norms.
arxiv
Carathéodory density of the Hurwitz metric on plane domains [PDF]
arXiv, 2020 It is well-known that the Carath\'eodory metric is a natural generalization of the Poincar\'e metric, namely, the hyperbolic metric of the unit disk. In 2016, the Hurwitz metric was introduced by D. Minda in arbitrary proper subdomains of the complex plane and he proved that this metric coincides with the hyperbolic metric when the domains are simply ...
arxiv
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Metrics for maternity unit staffing in low resource settings: Scoping review and proposed core indicator [PDF]
, 2023 William Stones, Anjali Nair
openalex +1 more source