Results 121 to 130 of about 1,662,806 (238)

Ptolemy’s inequality, chordal metric, multiplicative metric [PDF]

Pacific Journal of Mathematics, 1982
Klamkin, M. S., Meir, A.
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Differences across the lifespan between females and males in the top 20 causes of disease burden globally: a systematic analysis of the Global Burden of Disease Study 2021

The Lancet Public Health
Summary: Background: Sex and gender shape health. There is a growing body of evidence focused on comprehensively and systematically examining the magnitude, persistence, and nature of differences in health between females and males.
Vedavati Patwardhan, PhD, Gabriela F Gil, MPH, Alejandra Arrieta, MIDP, Jack Cagney, MSc, Erin DeGraw, MPH, Molly E Herbert, MSc, Mariam Khalil, MSc, Erin C Mullany, BA, Erin M O’Connell, BA, Cory N Spencer, MPH, Caroline Stein, PhD, Aiganym Valikhanova, PhD, Emmanuela Gakidou, ProfPhD, Luisa S Flor, PhD   +13 more
doaj   +1 more source

*metrics

, 2020
Lemke, Steffen, Zagovora, Olga, Weller, Katrin, Orth, Astrid, Beucke, Daniel, Stropel, Julius, Peters, Isabell   +6 more
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Health literacy and mental health: a national cross-sectional inquiry

Scientific Reports
Health literacy and mental health are among the most important issues in the modern health and era of public health. This study aimed to investigate the association between health literacy and mental health status.
Aliasghar Haeri-Mehrizi, Samira Mohammadi, Shahram Rafifar, Jila Sadighi, Ramin Mozaffari Kermani, Rahele Rostami, Akram Hashemi, Mahmoud Tavousi, Ali Montazeri   +8 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Simulated data for census-scale entity resolution research without privacy restrictions: a large-scale dataset generated by individual-based modeling [version 2; peer review: 1 approved, 2 approved with reservations]

Gates Open Research
Background Entity resolution (ER) is the process of identifying and linking records that refer to the same real-world entity. ER is a fundamental challenge in data science, and a common barrier to ER research and development is that the data fields used ...
Abraham Flaxman, Rajan Mudambi, Beatrix Haddock, Nathaniel Blair-Stahn, Alix Pletcher, Matt Kappel, Os Keyes, Syl Lutze, Steve Bachmeier, Alison Bowman, James Albright, Zeb Burke-Conte, Caroline Kinuthia   +12 more
doaj   +1 more source

Metrics, what metrics?

, 2014
Peer ...
openaire   +1 more source