Results 1 to 10 of about 149,141 (380)
Antimicrobial Resistance and Infection Control, 2019 Background Globally metronidazole and carbapenem resistance in anaerobic organisms is increasing necessitating continuous surveillance to guide selection of empirical treatment. In this study we have determined metronidazole resistance in anaerobes using
Yusra Shafquat +6 more
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Plasmid-mediated metronidazole resistance in Clostridioides difficile
Nature Communications, 2020 Cases of C. difficile (CD) resistant to metronidazole have been reported but the mechanism remains enigmatic. Here the authors identify a plasmid, which correlates with metronidazole resistance status in a large international collection of CD isolates ...
Ilse M. Boekhoud +9 more
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Resistance towards metronidazole in Blastocystis sp.: A pathogenic consequence.
PLoS ONE, 2019 Blastocsytis sp. is a protozoan parasite that has been linked to common gastrointestinal illnesses. Metronidazole, the first line therapy, was reported to show frequent inefficacy. Previously, Blastocystis sp.
Arutchelvan Rajamanikam +4 more
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bioRxiv, 2022 Severe outbreaks and deaths have been linked to the emergence and global spread of fluoroquinolone-resistant Clostridioides difficile over the past two decades. At the same time, metronidazole, a nitro-containing antibiotic, has shown decreasing clinical
A. O. Olaitan +13 more
semanticscholar +1 more source
Impact of prophylactic use of antimicrobials in abdominal surgery in two tertiary level hospitals [PDF]
Bangladesh Journal of Pharmacology, 2008 Post-surgical infections are polymicrobial and it is an important cause of morbidity and mortality. The combination of ciprofloxacin plus metronidazole as well as several ß-lactum based regimens are commonly used regimens for the treatment of patients ...
Shusmita Saha, Syed Ashrafuzzaman
doaj +3 more sources
Susceptibility testing of Helicobacter pylori: Comparison of E-test and Disk Diffusion for Metronidazole and Mutations in rdxA gene sequences of Helicobacter pylori strains [PDF]
Trends in Pharmaceutical Sciences, 2015 Metronidazole is a main stay of modern multidrug therapies for Helicobacter pylori (H. pylori) infection. Metronidazole resistance reduces the effectiveness of these combinations. Various methods have been used for the determination of the sensitivity of
laleh mahmoudi +4 more
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Applied Sciences, 2021 Diabetic foot ulcers are recognized to be a severe complication of diabetes, increasing the risk of amputation and death. The bacterial infection of Diabetic foot ulcers with virulent and resistant bacteria as Proteus mirabilis greatly worsens the wound ...
A. Khayyat +10 more
semanticscholar +1 more source
Journal of Antimicrobial Chemotherapy, 2021 Background Until recently, metronidazole was the first-line treatment for Clostridioides difficile infection and it is still commonly used. Though resistance has been reported due to the plasmid pCD-METRO, this does not explain all cases.
Ilse M. Boekhoud +19 more
semanticscholar +1 more source
Impact of previous metronidazole exposure on metronidazole-based second-line quadruple therapy for Helicobacter pylori infection [PDF]
The Korean Journal of Internal Medicine, 2020 Background/Aims The negative effects on the eradication success of Helicobacter pylori infection after previous exposure to macrolides, including clarithromycin on clarithromycin-based first-line therapy have been demonstrated.
Gil Ho Lee +6 more
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