Plasmid-mediated metronidazole resistance in Clostridioides difficile [PDF]
Nature Communications, 2020 Cases of C. difficile (CD) resistant to metronidazole have been reported but the mechanism remains enigmatic. Here the authors identify a plasmid, which correlates with metronidazole resistance status in a large international collection of CD isolates ...
Ilse M. Boekhoud +9 more
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Susceptibility testing of Helicobacter pylori: Comparison of E-test and Disk Diffusion for Metronidazole and Mutations in rdxA gene sequences of Helicobacter pylori strains [PDF]
Trends in Pharmaceutical Sciences, 2015 Metronidazole is a main stay of modern multidrug therapies for Helicobacter pylori (H. pylori) infection. Metronidazole resistance reduces the effectiveness of these combinations. Various methods have been used for the determination of the sensitivity of
laleh mahmoudi +4 more
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Impact of prophylactic use of antimicrobials in abdominal surgery in two tertiary level hospitals [PDF]
Bangladesh Journal of Pharmacology, 2008 Post-surgical infections are polymicrobial and it is an important cause of morbidity and mortality. The combination of ciprofloxacin plus metronidazole as well as several ß-lactum based regimens are commonly used regimens for the treatment of patients ...
Shusmita Saha, Syed Ashrafuzzaman
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Toxics, 2023 Long-term use of the nitroimidazole-derived antibiotic metronidazole has been associated with neuronal damage due to its ability to cross the blood–brain barrier.
Amira M. El-Moslemany +6 more
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Acute toxicity of metronidazole and its interaction with chlorpyrifos in chicks [PDF]
Iraqi Journal of Veterinary Sciences, 2021 Metronidazole is antimicrobial drug for human and animal use, The more characteristic side effect associated with use high dose of metronidazole is neurotoxic signs, some of these signs that recorded in animal represented by ataxia and tremor, there is ...
Douaa H. Alsanjary, Sawsan M. Amin
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Synthesis of New Cyclic Amines-Linked Metronidazole Derivatives as Possible Prodrugs
Iraqi Journal of Pharmaceutical Sciences, 2017 Certain cyclic amine derivatives of metronidazole via acetate spacer were prepared. Cyclic amines used are piperidine and piperazine to improve the physicochemical properties and reduce some of metronidazole side effects.
Maadh Q. Abdul-Kadir +2 more
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Impact of previous metronidazole exposure on metronidazole-based second-line quadruple therapy for Helicobacter pylori infection [PDF]
The Korean Journal of Internal Medicine, 2020 Background/Aims The negative effects on the eradication success of Helicobacter pylori infection after previous exposure to macrolides, including clarithromycin on clarithromycin-based first-line therapy have been demonstrated.
Gil Ho Lee +6 more
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Medical and Health Science Journal, 2020 ABSTRAK Tujuan: Membandingkan angka kekambuhan pengobatan Metronidazole tunggal dibandingkan kombinasi Metronidazole dan Probiotik pada Bacterial Vaginosis (BV). Metode: Pencarian data dilakukan pada database kedokteran (PUBMED, Cochrane Database)
risna ardianti mitavania, Azami Denas
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Assessment of the feasibility of the formulation of preparation for the growth inhibition of metronidazole-resistant strains isolated from the periodontal pockets [PDF]
Vojnosanitetski Pregled, 2005 Introduction. Topical metronidazole benzoate preparations, applied directly into the space between the teeth and periodontal tissue, are the treatment of choice for periodontal pockets.
Toskić-Radojičić Marija +3 more
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Metronidazole-induced Encephalopathy
IDCases, 2019 Metronidazole is commonly used in the treatment of anaerobic infections. While neuropathy is known to be associated with metronidazole, encephalopathy has been rarely reported.
Htay Phyu +2 more
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