Synthesis of New Cyclic Amines-Linked Metronidazole Derivatives as Possible Prodrugs
Iraqi Journal of Pharmaceutical Sciences, 2017 Certain cyclic amine derivatives of metronidazole via acetate spacer were prepared. Cyclic amines used are piperidine and piperazine to improve the physicochemical properties and reduce some of metronidazole side effects.
Maadh Q. Abdul-Kadir +2 more
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Applied Water Science, 2023 Metronidazole is well-known antibiotic which, globally, ranks high in popular usage. Therefore, traces of residues of this antibiotic were identified in aquatic bodies. A photosynthetic cyanobacterium, of the microalgae category, S.
Tariq J Al-Musawi +2 more
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Metronidazole-induced neurotoxicity: Is iron a contributing factor? [PDF]
Mediterranean Journal of Pharmacy and Pharmaceutical SciencesMetronidazole-induced neurotoxicity is a rising challenge in managing susceptible infections. The mechanisms involved in metronidazole-induced neurotoxicity are not fully unraveled.
Moses W. Bariweni
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Metronidazole-associated mood changes: A case report [PDF]
Exploratory Research in Clinical and Social PharmacyMetronidazole is an antibiotic used in the treatment of wide array of bacterial infections.This case report describes a 55-year-old female patient taking treatment for sigmoid non-complicated diverticulitis who developed an unanticipated adverse drug ...
Lamis R. Karaoui +2 more
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Investigation of the Antitrichomonal Activity of Cinnamaldehyde, Carvacrol and Thymol and Synergy with Metronidazole [PDF]
Türkiye Parazitoloji DergisiObjective: Trichomonas vaginalis is a sexually transmitted protozoan parasite that usually causes infections in women. Metronidazole is used as the first choice in the treatment of this parasitic disease, but there is a need for new drugs since 1980’s ...
Yener Özel +4 more
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Metronidazole-induced encephalopathy in a patient with Crohn's disease
Intestinal Research, 2017 Metronidazole is a widely used antibiotic for the treatment of anaerobic bacterial infections. Metronidazole-induced encephalopathy (MIEP) is a rare but potentially reversible disease.
Jihye Kim +9 more
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nim gene-independent metronidazole-resistant Bacteroides fragilis in surgical site infections
GMS Hygiene and Infection Control, 2017 Background: is the most common anaerobic pathogen isolated from surgical site infections (SSIs). Metronidazole resistance is increasing and the mechanisms of resistance are not clear in some isolates.
Akhi, Mohammad Taghi +7 more
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Impact of prophylactic use of antimicrobials in abdominal surgery in two tertiary level hospitals [PDF]
Bangladesh Journal of Pharmacology, 2008 Post-surgical infections are polymicrobial and it is an important cause of morbidity and mortality. The combination of ciprofloxacin plus metronidazole as well as several ß-lactum based regimens are commonly used regimens for the treatment of patients ...
Shusmita Saha, Syed Ashrafuzzaman
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Susceptibility testing of Helicobacter pylori: Comparison of E-test and Disk Diffusion for Metronidazole and Mutations in rdxA gene sequences of Helicobacter pylori strains [PDF]
Trends in Pharmaceutical Sciences, 2015 Metronidazole is a main stay of modern multidrug therapies for Helicobacter pylori (H. pylori) infection. Metronidazole resistance reduces the effectiveness of these combinations. Various methods have been used for the determination of the sensitivity of
laleh mahmoudi +4 more
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Toxics, 2023 Long-term use of the nitroimidazole-derived antibiotic metronidazole has been associated with neuronal damage due to its ability to cross the blood–brain barrier.
Amira M. El-Moslemany +6 more
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