Results 141 to 150 of about 112,423 (291)

Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma

Allergy, EarlyView.
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud, Emil M. Pallesen, Ziao Zeng, Martin R. J. Namini, Chella Krishna Vadivel, Lise Mette Rahbek Gjerdrum, Lang Yan, Sana Ahmad, Lise M. Lindahl, Michael Bzorek, Maria R. Kamstrup, Saptaswa Dey, Sisse Rye Ostrowski, Erik Sørensen, Pia Rantakari, Charlotte Menne Bonefeld, Carsten Geisler, Anders Woetmann, Riitta Lahesmaa, Lars Iversen, Peter Wolf, Thomas Litman, Terkild B. Buus, Niels Ødum   +23 more
wiley   +1 more source

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey, Knut Brockow, Annick Barbaud, Charlotte G. Mortz, Gianfranco Calogiuri, Asli Gelincik, Osman O. Yeğit, Alla Nakonechna, Annette Wagner, Rik Schrijvers, Toon Ieven   +10 more
wiley   +1 more source

Practice Patterns and Outcomes of Preoperative Mechanical Bowel Preparation and Oral Antibiotics for Restorative Elective Colorectal Surgery: Nationwide Analysis of the ACS‐NSQIP Australian Data

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background There is increasing evidence that the addition of preoperative antibiotics (OAB) reduces infectious complications after colorectal surgery. To understand practice patterns in Australia, Australian hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program (ACS‐NSQIP) collecting targeted
Joseph Do Woong Choi, Nguyen Huynh, Kalai Kuppusamy, David Clark, Richard Bryant, Aleksandra Edmundson, Rebecca Radford, Andrew Gilmore, Yasser Farooque, Elaine Zhang, Nimmi Kumar, Matthew Morgan, Neil Merrett, Mingjuan Zeng, Bruce Hodge, Andrew Sutherland, Jimmy Chin Li Lee, Andrea Giles, Diana Tam, Emma Plecas, Boris Strekozov, Chantel Gablonski, Shella de Robles, Jennifer Hearn, Gregory Nolan, Michelle Cooper, Rebecca Boyle, Kelvin Kwok, Ian Incoll, Caitlin Queripel, Amy Cao, Nimalan Pathma‐Nathan, Toufic El‐Khoury, Arthur J. Richardson, Kerry Hitos, James Wei Tatt Toh   +35 more
wiley   +1 more source

Retinoic Acid Signalling Regulates Zebrafish Tooth Germ Repair Following Injury

Cell Proliferation, EarlyView.
Retinoic acid signalling may regulate the repair processes in a tooth germ injury model using Tg(scpp5:Dendra2‐NTR) zebrafish and the nitroreductase (NTR)/metronidazole (MTZ) system. ABSTRACT Although the role of retinoic acid (RA) signalling in odontogenesis is well established, its involvement in the repair of injured tooth germs remains unclear.
Qiqi Liu, Zhenan Zhang, Weifeng Hao, Chunyan Zhou, Deqin Yang   +4 more
wiley   +1 more source

Letter to the editor regarding: “A rare clinical presentation of metronidazole-induced dysarthria: A Case report with literature review”

Radiology Case Reports
Erin Jensen
doaj   +1 more source

National Delphi consensus on laser and energy‐based treatments for rosacea

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Various treatments are available for rosacea, including lasers and energy‐based devices (EBDs). However, the specific role of lasers and EBDs in rosacea management remains insufficiently defined in Germany. The aim of the study was to develop a comprehensive expert consensus on the use of lasers and EBDs in the treatment of rosacea ...
Lynhda Nguyen, Nikolaus Seeber, Uwe Paasch, Martin Schaller, Claudia Borelli, Syrus Karsai, Gerd Kautz, Tanja C. Fischer, Michael Drosner, Stefan Hammes, Konstantin Feise, Christian Raulin, Martina Kerscher, Gerd Gauglitz, Jens M. Baron, Stefan W. Schneider, Katharina Herberger   +16 more
wiley   +1 more source

A new branch of mammalian vitamin B6 metabolism: AKR1C‐mediated conversion of pyridoxal to pyridoxine and 4‐pyridoxolactone

The FEBS Journal, EarlyView.
Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito, Yasuyuki Kitaura, Kyoka Iino, Kazuya Toriumi, Hyunah Noh, Naoya Ogawa, Makoto Arai, Hisashi Hemmi, Tomokazu Ito   +8 more
wiley   +1 more source

Empiric antibiotics for sepsis [PDF]

, 2018
Buckman, Sara A, Mazuski, John E, Turnbull, Isaiah R   +2 more
core   +2 more sources

Evaluation of the performance of ChatGPT‐4 and ChatGPT‐4o as a learning tool in endodontics

International Endodontic Journal, EarlyView.
Abstract Aims The aim of this study was to evaluate the accuracy and consistency of responses given by two different versions of Chat Generative Pre‐trained Transformer (ChatGPT), ChatGPT‐4, and ChatGPT‐4o, to multiple‐choice questions prepared from undergraduate endodontic education topics at different times of the day and on different days ...
Esra Arılı Öztürk, Ceren Turan Gökduman, Burhan Can Çanakçi   +2 more
wiley   +1 more source

Intravaginal Metronidazole for the Prevention of Post-Cesarean Endometritis

مجله دانشکده پزشکی اصفهان, 2009
Background: Postpartum endometritis is an important cause of maternal morbidity after cesarean section. Prophylactic antibiotic therapy reduces the risk by approximately 60%.
Leila Sekhavat, Afsarsadat Tabatabaii
doaj