Results 181 to 190 of about 65,902 (259)

Multi-Antibiotic Porous Systems for Tailored Drug Delivery in Dentistry: Formulation Strategy, Physicochemical Properties, and Release. [PDF]

Pharmaceutics
Biernat M, Sylla A, Stępień KA, Giebułtowicz J, Ciołek L, Szterner P, Tymowicz-Grzyb P, Kózka B, Olczak-Kowalczyk D.   +8 more
europepmc   +1 more source

Preserved Spermatogenesis and Hormonal Function in Men Receiving a Pretomanid Regimen (BPaMZ) for Pulmonary Drug‐Resistant Tuberculosis

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 501-509, August 2026.
Pretomanid is a component of the World Health Organization‐recommended treatment regimen for drug‐resistant tuberculosis in patients aged ≥ 14 years. While preclinical rodent studies identified testicular toxicity as a potential clinical liability at elevated doses, no corresponding effects were observed in nonhuman primates nor clinical hormone ...
Pauline Howell, Antonio Lombardi, William Brumskine, Lali Mikiashvili, Kim Boekelheide, Joanna Moreira, Alda Holsta, Matthew Betteridge, Lindsay Thompson, Angela Crook, Paul Bruinenberg, Maria Beumont, Eugene Sun, Francesca Conradie   +13 more
wiley   +1 more source

Intestinal epithelial SETD2 maintains gut microbial homeostasis to attenuate colitis

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
• SETD2 deficiency in intestinal epithelial cells (IECs) drives REG3 lectins overproduction and triggers profound gut microbiota dysbiosis. • SETD2 deficiency increased chromatin accessibility and induced H3K4me3 enrichment at REG3 genes. • Supplementation with healthy‐like gut microbiota significantly ameliorated the exacerbated colitis induced by ...
Jing Feng, Ziyi Wang, Yue Xu, Jinjin Peng, Che Xu, Qingxin Xie, Yuyi Li, Wangshuang Chen, Jiaqing Chen, Xingyu Wang, Wei‐Qiang Gao, Li Li, Xiangjun Meng   +12 more
wiley   +1 more source

Metronidazole is an effective method of analgesia following haemorrhoidectomy: a systematic review and meta-analysis. [PDF]

Int J Colorectal Dis
O'Mahony A, Cullinane C, MacCurtain BM, Peirce C, Condon E, Coffey JC, Fleming CA.   +6 more
europepmc   +1 more source

The Impact of Oral‐Gut Microbiota Structure and Its Manipulation on RA Development and Management

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
(A) Schematic representation of oral–gut microbiota composition in health and rheumatoid arthritis (RA), highlighting the enrichment of beneficial microorganisms (green) under healthy conditions and the expansion of pathogenic microorganisms (orange) in RA‐associated dysbiosis.
Parisa Ahmadi, Mahmoud Mahmoudi, Sina Mozaffari‐Jovin, Ramiar Kamal Kheder, Tola Abdulsattar Faraj, Samaneh Mollazadeh, Jafar Hajavi, Hanieh Kolahdooz, Seyed‐Alireza Esmaeili   +8 more
wiley   +1 more source

First-in-Human Randomized Controlled Pilot Trial of a Maxillofacial Drug Delivery Platform for Low-Dose Systemic Delivery. [PDF]

Cureus
Ramachandran S, Kandasamy R, Verma K, Ashokan PL, Murugan J, Sudhakar J, Janardhanan HA, Ur A.   +7 more
europepmc   +1 more source

MYC in Oncogenesis and Therapeutic Implications

MedComm, Volume 7, Issue 8, August 2026.
The MYC oncogene family (c‐MYC, N‐MYC, L‐MYC) functions as a central transcriptional hub orchestrating cancer progression through multiple interconnected pathways. This graphical abstract illustrates MYC's role as a multidimensional regulator positioned at the nexus of tumor microenvironment remodeling, metabolic reprogramming, and therapeutic ...
Na Zhang, Li Wei, Cuiping Tang, Peilong Lai, Wenbin Zhong, Hua You   +5 more
wiley   +1 more source

Antibiotic resistance in odontogenic infections: A systematic review of current evidence and implications for guideline-based therapy. [PDF]

Clin Oral Investig
Schmid AI, Werkmeister R, Al-Nawas B, Heider J.   +3 more
europepmc   +1 more source

Recent Advancements in PVDF‐Based Hybrid Metal Oxide Nanocomposites as Photocatalysts for Environmental Remediation: A Critical Review

Nano Select, Volume 7, Issue 8, August 2026.
ABSTRACT Polyvinylidene Flouride (PVDF)‐based hybrid metal oxides have emerged as significant materials in the domain of wastewater treatment. This review article provides a comprehensive outline of the synthesis, properties, and applications of PVDF‐based hybrid metal oxide composites with a focus on their enhanced performance in wastewater treatment ...
Danish Umer, Maryam Bibi, Nimra Nadeem, Zubair Khaliq, Muhammad Bilal Qadir, Muhammad Zahid, Muhammad Wakil Shahzad, Muhammad Sultan, Rana Muhammad Asif Kanwar, Asim Jilani   +9 more
wiley   +1 more source