Results 51 to 60 of about 86,298 (291)

Coenzyme-Q10 Reverses Metronidazole-induced Cognitive Dysfunction in Rats [PDF]

open access: yesJournal of Advanced Pharmacy Research
Objective: Metronidazole, an essential component in surgical prophylaxis and treatment of several infections is faced with an increase in reports of neurotoxic outcomes.
Moses Bariweni   +2 more
doaj   +1 more source

Risk Factors for Treatment Failure and Recurrence after Metronidazole Treatment for Clostridium difficile-associated Diarrhea

open access: yesGut and Liver, 2010
Background/Aims: The incidence of treatment failure or recurrence of Clostridium difficile-associated diarrhea (CDAD) following metronidazole treatment has increased recently. We studied the treatment failure, recurrence rate, and risk factors predictive
doaj   +1 more source

METRONIDAZOLE GEL EFFECT ON RATS WITH BACTERIA-INDUCED PERIODONTITIS

open access: yesODONTO: Dental Journal, 2020
Background: Periodontitis is an inflammatory disease in the periodontal tissue and causes progressive tissue damage. Tissue Inhibitor of Matrix Metalloproteinases-1 (TIMP-1) is directly responsible for the pathogenesis of periodontal diseases.
Muhamat Muhtar S. Abdurrohman   +1 more
doaj   +1 more source

Giardia duodenalis: Exposure to metronidazole inhibits competitive interactions between isolates of the parasite in vitro [PDF]

open access: yes, 1996
The competitive interactions of genetically distinct isolates of Giardia duodenalis with different growth rates were studied in vitro. Electrophoretic analysis of mixed cultures showed that competition between 2 cloned isolates occurs under normal in ...
Meloni, B.P.   +5 more
core  

Gut Microbiota‐Derived Indole‐3‐Acetaldehyde Contributes to the Disease‐Alleviating Effects of Kurarinone in Experimental Autoimmune Encephalomyelitis

open access: yesAdvanced Science, EarlyView.
Kurarinone ameliorates EAE via the gut microbiota‐indole‐3‐acetaldehyde‐AhR axis. Kurarinone reshapes gut microbiota and increases Akkermansia muciniphila, which promotes intestinal indole‐3‐acetaldehyde production. Indole‐3‐acetaldehyde crosses the intestinal barrier, activates AhR in CD4+ T cells, upregulates SOCS1/3, inhibits JAK2 and STAT3/4 ...
Xinyan Han   +11 more
wiley   +1 more source

Metronidazole induced neurotoxicity: a case report [PDF]

open access: yes, 2023
Metronidazole is a well-known antimicrobial agent, used for the treatment of anaerobic bacterial and protozoal infections. It is generally well tolerated with common side effects like nausea, dizziness, headache and metallic taste in the mouth.
Sinha, Rani I.   +4 more
core   +1 more source

Small Intestinal Bacterial Overgrowth Following Gastrointestinal Cancer Surgery: Current Evidence and Future Perspectives

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Small intestinal bacterial overgrowth (SIBO) has recently gained increasing attention as a potential cause of postoperative gastrointestinal symptoms following gastrointestinal cancer surgery. Surgical procedures can disrupt normal gastrointestinal physiology through anatomical reconstruction, impaired motility, reduced gastric acid secretion,
Toru Aoyama   +2 more
wiley   +1 more source

Bioadhesive Controlled Metronidazole Release Matrix Based on Chitosan and Xanthan Gum

open access: yesMarine Drugs, 2010
Metronidazole, a common antibacterial drug, was incorporated into a hydrophilic polymer matrix composed of chitosan xanthan gum mixture. Hydrogel formation of this binary chitosan-xanthan gum combination was tested for its ability to control the release ...
Ala’a F. Eftaiha   +6 more
doaj   +1 more source

Non-Surgical Periodontal Therapy with Adjunctive Amoxicillin/Metronidazole or Metronidazole When No Aggregatibacter actinomycetemcomitans Is Detected-A Randomized Clinical Trial. [PDF]

open access: yes, 2020
BACKGROUND The aim was to compare two different systemic antibiotics regimens adjunctive to non-surgical periodontal therapy when Aggregatibacter actinomycetemcomitans was not detected in the subgingival biofilm.
Sigrun Eick   +8 more
core   +2 more sources

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed   +7 more
wiley   +1 more source

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