Results 71 to 80 of about 149,141 (380)
Advanced Science, EarlyView.Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang +16 more
wiley +1 more source
Metronidazole-induced encephalopathy
South African Journal of Radiology, 2021 Metronidazole is a widely used antibacterial and antiprotozoal agent for a number of conditions. Whilst its more common gastrointestinal side effects are well known, neurotoxicity remains under-recognised. Both central and peripheral neurological side effects have been described.
Adam Mahomed +4 more
openaire +6 more sources
Metronidazole Causes Skeletal Muscle Atrophy and Modulates Muscle Chronometabolism
International Journal of Molecular Sciences, 2018 Antibiotics lead to increased susceptibility to colonization by pathogenic organisms, with different effects on the host-microbiota relationship. Here, we show that metronidazole treatment of specific pathogen-free (SPF) mice results in a significant ...
Ravikumar Manickam +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu +14 more
wiley +1 more source
EFFECT OF METRONIDAZOLE (FLAGYL) ON RBC, WBC AND ACTIVITY OF THREE ENZYMES IN THE BLOOD SERUM OF ALBINO FEMALE MICE [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2014 Metronidazole is a drug used against bacteria and protozoa in the body. The toxicity of metronidazole to kidney ,liver and other organs has been shown in some studies. The purpose of this study was to examine the effects of metronidazole (200,400 and 600
ABED.A. THAKER +2 more
doaj +1 more source
Urinary and faecal N-methylhistamine concentrations do not serve as markers for mast cell activation or clinical disease activity in dogs with chronic enteropathies [PDF]
, 2014 This study sought to correlate faecal and urinary N-methylhistamine (NMH) concentrations with resting versus degranulated duodenal mast cell numbers in dogs with chronic enteropathies (CE), and investigate correlations between intestinal mast cell ...
Allenspach, K +5 more
core +3 more sources
Advanced Science, EarlyView.Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu +7 more
wiley +1 more source
Treatment of helicobacter pylori infection in atrophic gastritis [PDF]
, 2018 Helicobacter pylori (Hp) is a major human pathogen causing chronic, progressive gastric mucosal damage and is linked to gastric atrophy and cancer. Hp-positive individuals constitute the major reservoir for transmission of infection.
Annibale, B, Carabotti, M, Lahner, E
core +1 more source
Advanced Science, EarlyView.Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie +9 more
wiley +1 more source
Health outcomes of statin users compared to non-users with Clostridium difficile infection [PDF]
, 2017 Background: Clostridium difficile infection (CDI) is the most common cause of nosocomial diarrhea, and the primary cause of healthcare-associated infections in the United States. Statins have beneficial effects independent of their lipid-lowering effects;
Argamany, Jacqueline Rose
core +1 more source