Results 1 to 10 of about 20,586 (243)

A multilayer network model of neuron-astrocyte populations in vitro reveals mGluR5 inhibition is protective following traumatic injury [PDF]

, 2022
Margaret E. Schroeder, Danielle S. Bassett, David F. Meaney   +2 more
openalex   +1 more source

Environmental condition alters amphetamine self-administration: role of the MGluR5 receptor and schedule of reinforcement

, 2015
David L. Arndt, K. C. Johns, Z. K Dietz, Mary E. Cain   +3 more
openalex   +2 more sources

Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α

Cell Reports
Summary: Little is known of the brain mechanisms that mediate sex-specific autism symptoms. Here, we demonstrate that deletion of the autism spectrum disorder (ASD)-risk gene, Pten, in neocortical pyramidal neurons (NSEPten knockout [KO]) results in ...
Gemma Molinaro, Jacob E. Bowles, Katilynne Croom, Darya Gonzalez, Saba Mirjafary, Shari G. Birnbaum, Khaleel A. Razak, Jay R. Gibson, Kimberly M. Huber   +8 more
doaj   +1 more source

Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory [PDF]

, 2018
Sophie Lepannetier, Roberta Gualdani, Sabrina Tempesta, Olivier Schakman, François Seghers, Anna Kreis, Xavier Yerna, Amina Slimi, Marie de Clippele, Nicolas Tajeddine, Thomas Voets, Robin S. Bon, David J. Beech, Fadel Tissir, Philippe Gailly   +14 more
openalex   +1 more source

Metabotropic glutamate receptor 5 may be involved in macrophage plasticity

Biological Research
Background Macrophages are a functionally heterogeneous cell population and depending on microenvironments they polarize in two main groups: M1 and M2. Glutamic acid and glutamate receptors may participate in the regulation of macrophage plasticity.
Lali Shanshiashvili, Elene Tsitsilashvili, Nino Dabrundashvili, Irine Kalandadze, David Mikeladze   +4 more
doaj   +1 more source

Case report: Overlapping syndrome mimicking infectious meningoencephalitis in a patient with coexistent MOG, NMDAR, mGluR5 antibody positivity

, 2022
Jie Fu, Lilei Peng, Yang Yang, Yang Xie, Zuoxiao Li, Benbing Rong   +5 more
openalex   +1 more source

Pharmacological and Anatomical Evidence for an Interaction Between mGluR5- and GABAA α1-Containing Receptors in the Discriminative Stimulus Effects of Ethanol

, 2020
Joyce Besheer, Clyde W. Hodge
openalex   +1 more source

The PDZ Scaffold NHERF-2 Interacts with mGluR5 and Regulates Receptor Activity [PDF]

, 2006
Maryse Paquet, Matthew J. Asay, Sami R. Fam, Hiroyuki Inuzuka, Amanda M. Castleberry, Heide Oller, Yoland Smith, C. Chris Yun, Stephen F. Traynelis, Randy A. Hall   +9 more
openalex   +1 more source

Aβ pathology downregulates brain mGluR5 density in a mouse model of Alzheimer

, 2018
Minkyung Lee, Hae‐June Lee, In Suh Park, Ji Ae Park, Yeon Kwon, Young Hoon Ryu, Chul Hoon Kim, Joo Hyun Kang, In Young Hyun, Kyo Chul Lee, Jae Yong Choi   +10 more
openalex   +2 more sources

α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B

, 2017
Diana G. Ferreira, Mariana Temido‐Ferreira, Hugo Vicente Miranda, Vânia L. Batalha, Joana E. Coelho, Éva M. Szegő, Inês Marques-Morgado, Sandra H. Vaz, Jeong Seop Rhee, Matthias Schmitz, Inga Zerr, Luı́sa V. Lopes, Tiago F. Outeiro   +12 more
openalex   +2 more sources