Results 61 to 70 of about 505,271 (361)
A Review of Suggested Mechanisms of MHC Odor Signaling
Although an individual’s mix of MHC immune genes determines its resistance, finding MHC-dependent mate choice occurred by accident in inbred mice. Inbred mice prefer MHC dissimilar mates, even when the choice was restricted to urine.
Manfred Milinski
doaj +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Chaperone-mediated MHC-I peptide exchange in antigen presentation
This work focuses on molecules that are encoded by the major histocompatibility complex (MHC) and that bind self-, foreign- or tumor-derived peptides and display these at the cell surface for recognition by receptors on T lymphocytes (T cell receptors ...
Jiansheng Jiang+2 more
doaj +1 more source
Smooth Muscle Myosin Heavy Chain Isoform Distribution in the Swine Stomach [PDF]
To evaluate the distribution of smooth muscle myosin heavy chain isoforms (SMB, with head insert), we examined frozen sections from the various regions of swine stomachs using isoform-specific antibodies.
Eddinger, Thomas J., Parisi, Jonathan A.
core +1 more source
MHC Restriction of V-V Interactions in Serum IgG [PDF]
According to Jerne’s idiotypic network hypothesis, the adaptive immune system is regulated by interactions between the variable regions of antibodies, B cells, and T cells.
Earnest Leung, Geoffrey W. Hoffmann
core +2 more sources
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
Biological Consequences of MHC-II Expression by Tumor Cells in Cancer
Immunotherapy has emerged as a key pillar of cancer treatment. To build upon the recent successes of immunotherapy, intense research efforts are aimed at a molecular understanding of antitumor immune responses, identification of biomarkers of ...
M. Axelrod+3 more
semanticscholar +1 more source
Infection is inconceivable without T cells. T cells not only eliminate virus-infected cells and participate in the formation of immunological memory, but also indirectly modulate the humoral response through the selection and maintenance of specific B ...
Mariia A. Salnikova, Yu. B. Lebedev
doaj +1 more source
Exploring Vocational Evaluation Practices following Traumatic Brain Injury
Background. Individuals with traumatic brain injury (TBI) face many challenges when attempting to return to work (RTW). Vocational evaluation (VE) is a systematic process that involves assessment and appraisal of an individual’s current work-related ...
Christina Dillahunt-Aspillaga+6 more
doaj +1 more source
Interpreting BERT architecture predictions for peptide presentation by MHC class I proteins [PDF]
The major histocompatibility complex (MHC) class-I pathway supports the detection of cancer and viruses by the immune system. It presents parts of proteins (peptides) from inside a cell on its membrane surface enabling visiting immune cells that detect non-self peptides to terminate the cell.
arxiv