Results 51 to 60 of about 551,654 (347)

Expression of CD226 is associated to but not required for NK cell education [PDF]

, 2017
DNAX accessory molecule-1 (DNAM-1, also known as CD226) is an activating receptor expressed on subsets of natural killer (NK) and T cells, interacts with its ligands CD155 or CD112, and has co-varied expression with inhibitory receptors. Since inhibitory
Bernhardt, Günter, Brodin, Petter, Chambers, Benedict J, Colonna, Marco, Gilfillan, Susan, Höglund, Petter, Kadri, Nadir, Kärre, Klas, Snäll, Johanna, Wagner, Arnika K   +9 more
core   +2 more sources

Alu elements within the human major histocompatibility class I region in the Comoros Islands: genetic variation and population relationships

Annals of Human Biology, 2019
Background: Alu elements are attractive markers for population genetics, disease, forensics and paternity analyses, due to their particular characteristics.
Said Nassor Abeid, Majida Motrane, Hamid Farhane, Nourdin Harich   +3 more
doaj   +1 more source

An evaluation of specialist mentoring for university students with autism spectrum disorders and mental health conditions [PDF]

, 2017
Mentoring is often recommended to universities as a way of supporting students with autism spectrum disorders (ASD) and/or mental health conditions (MHC), but there is little literature on optimising this support.
James, Alana I., Lucas, Rebecca
core   +2 more sources

Longitudinal tracking of T-cell repertoire reveals long-lasting CD4⁺ yellow fever specific clone cluster

Инфекция и иммунитет
Infection is inconceivable without T cells. T cells not only eliminate virus-infected cells and participate in the formation of immunological memory, but also indirectly modulate the humoral response through the selection and maintenance of specific B ...
Mariia A. Salnikova, Yu. B. Lebedev
doaj   +1 more source

Diversity of MHC IIB genes and parasitism in hybrids of evolutionarily divergent cyprinoid species indicate heterosis advantage

Scientific Reports, 2021
The genes of the major histocompatibility complex (MHC) are an essential component of the vertebrate immune system and MHC genotypes may determine individual susceptibility to parasite infection.
Andrea Šimková, Lenka Gettová, Kristína Civáňová, Mária Seifertová, Michal Janáč, Lukáš Vetešník   +5 more
doaj   +1 more source

MHC proteins confer differential sensitivity to CTLA-4 and PD-1 blockade in untreated metastatic melanoma

Science Translational Medicine, 2018
Loss of membrane MHC class I protein expression in most of tumor cells in advanced melanomas predicts primary resistance to anti–CTLA-4, but not anti-PD1, treatment.
Scott J Rodig, Scott J Rodig, D. Gusenleitner, D. Jackson, E. Gjini, A. Giobbie-Hurder, Chelsea Jin, Han Chang, S. Lovitch, C. Horak, J. Weber, J. Weirather, J. Wolchok, M. Postow, M. Postow, A. Pavlick, J. Chesney, F. Hodi   +17 more
semanticscholar   +1 more source

A novel luciferase immunosorbent assay performs better than a commercial enzyme-linked immunosorbent assay to detect MERS-CoV specific IgG in humans and animals

Biosafety and Health, 2019
The Middle East respiratory syndrome (MERS) is a lethal zoonosis caused by MERS coronavirus (MERS-CoV) and poses a significant threat to public health worldwide.
Wenling Wang, Tianyu Wang, Yao Deng, Peihua Niu, Ruhan A, Jincun Zhao, Malik Peiris, Shixing Tang, Wenjie Tan   +8 more
doaj   +1 more source

Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours [PDF]

, 2016
Natural killer (NK) lymphocytes are part of the innate immune system and are important in immune protection against tumourigenesis. NK cells display a broad repertoire of activating and inhibitory cell surface receptors that regulate NK cell activity ...
Filtjens, Jessica, Keirsse, Jiri, Kerre, Tessa, Leclercq, Georges, Plum, Jean, Taghon, Tom, Taveirne, Sylvie, Van Acker, Aline, Van Ammel, Els, Van Ginderachter, Jo A, Vandekerckhove, Bart   +10 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Smokers with Self-Reported Mental Health Conditions: A Case for Screening in the Context of Tobacco Cessation Services. [PDF]

PLoS ONE, 2016
People with mental health conditions (MHC) smoke at high rates and many die prematurely from smoking-related illnesses. Smoking cessation programs, however, generally do not screen for MHC.
Gary J Tedeschi, Sharon E Cummins, Christopher M Anderson, Robert M Anthenelli, Yue-Lin Zhuang, Shu-Hong Zhu   +5 more
doaj   +1 more source