Results 211 to 220 of about 277,895 (333)

Identification of a recurrent pattern of false-positivity by Luminex HLA MHC class I single antigen bead testing

, 2020
Christina L. Dean, Scott M. Krummey, Howard M. Gebel, Robert A. Bray, Harold C. Sullivan   +4 more
openalex   +2 more sources

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

Advanced Science, EarlyView.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen, Zhenzhen Wang, Liqiang Song, Qianqian Chen, Hang Zhang, Tao Pan, Jianli Pan, Sheng Zhao, Ting Shang, Hong'en Xu, Xing Lv, Jing Li, Fei Kang, Yongzhan Nie, Feng Zhao, Lei Shi, Zheng Wang   +16 more
wiley   +1 more source

Presenilin/γ-secretase and α-secretase-like peptidases cleave human MHC Class I proteins [PDF]

, 2006
Bryce W. Carey, Doo Y. Kim, Dora M. Kovacs   +2 more
openalex   +1 more source

METTL5 Enables Immune Evasion of Liver Cancer via Chemokine mRNA Translation Regulation

Advanced Science, EarlyView.
METTL5 reshapes the tumor immune microenvironment through ribosome 18S rRNA m6A modification to regulate the translation of chemokine mRNA. Targeting METTL5‐mediated immunosuppression unleashes anti‐tumor immunity and improves the efficacy of anti‐PD‐1 therapy.
Shuang Li, Xiao Zhao, Tongtong Song, Qiaoyi Chen, Yanqing Wu, Yuting Zhang, Jingying Chen, Yifan Wu, Bin Li, Xinyue Zhang, Zihao Dai, Lixia Xu, Yubin Xie, Alfred Sze‐Lok Cheng, Jianping Guo, Ming Kuang, Shuibin Lin, Zhenwei Peng, Sui Peng, Xuezhen Zeng   +19 more
wiley   +1 more source

Clinical and immunological spectrum of MHC class I deficiency: insights from a long-term cohort with two novel mutations. [PDF]

Front Immunol
Haskologlu S, Ikinciogullari A, Islamoglu C, Bal SK, Bayrakoglu D, Erdem S, Karahan ZC, Ardeniz O, Aytekin C, Heper A, Ceylaner S, Dogu F.   +11 more
europepmc   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Augmented MHC Class I on Professional Antigen-Presenting Cells and Enhanced Cytokine Production by CD8⁺ T Cells in Type 2 Diabetes Mellitus. [PDF]

Eur J Immunol
Liu S, Jayasinghe T, Kamińska D, Xu X, Ren X, Jiao Y, Kong Y, Li X, Li K, Antoniou AN, Li W, Błażewska K, Gendaszewska-Darmach E, Xu J, Garstka MA.   +14 more
europepmc   +1 more source

Figure S9 from Hypoxia-Induced Long Noncoding RNA <i>HIF1A-</i><i>AS2</i> Regulates Stability of MHC Class I Protein in Head and Neck Cancer

Tsai‐Tsen Liao, Yu-Hsien Chen, Zih-Yu Li, An-Ching Hsiao, Ya-Li Huang, Ruo-Xin Hao, Shyh‐Kuan Tai, Pen‐Yuan Chu, Jing-Wen Shih, Hsing‐Jien Kung, Muh‐Hwa Yang   +10 more
openalex   +1 more source

Contribution of Gli1+ Adventitial Stem Cells to Smooth Muscle Cells in Atherosclerosis and Vascular Injury

Advanced Science, EarlyView.
Gli1+ adventitial stem cells (ASCs) have been thought to generate smooth muscle cells (SMCs) in atherosclerosis. Using a dual‐recombinase lineage tracing to exclude ectopic labeling, Wang et al. found that Gli1+ ASCs do not contribute to SMCs in atherosclerotic plaques.
Haixiao Wang, Xiuzhen Huang, Jialing Mou, Enci Wang, Yan Li, Wenjuan Pu, Yao Xie, Xiaoling Guo, Lixin Wang, Maoping Chu, Bin Zhou, Chao Niu   +11 more
wiley   +1 more source

Reversal of tumour immune evasion via enhanced MHC-Class-I antigen presentation by a dual-functional RNA regulated system. [PDF]

Mol Cancer
Meng C, Zhang H, Yi X, Kong G, Zhang X, Wang B, Xu Y, Qi H, Wu Q, Zhang K, Cao J, Lin X, Feng H, Chen J, Zheng S, Gu Z, Li H, Ling Q.   +17 more
europepmc   +1 more source