Results 21 to 30 of about 275,601 (334)

Tight Regulation of Major Histocompatibility Complex I for the Spatial and Temporal Expression in the Hippocampal Neurons

Frontiers in Cellular Neuroscience, 2021
The expression and function of immune molecules, such as major histocompatibility complex (MHC), within the developing and adult brain have been discovered over the past few years.
Yuqing Shen, Yuqing Shen, Jianqiong Zhang, Jianqiong Zhang, Jianqiong Zhang   +4 more
doaj   +1 more source

The Major Histocompatibility Complex of Old World Camels—A Synopsis

Cells, 2019
This study brings new information on major histocompatibility complex (MHC) class III sub-region genes in Old World camels and integrates current knowledge of the MHC region into a comprehensive overview for Old World camels.
Martin Plasil, Sofia Wijkmark, Jean Pierre Elbers, Jan Oppelt, Pamela Anna Burger, Petr Horin   +5 more
doaj   +1 more source

Evidence for directional selection at a novel major histocompatibility class I marker in wild common frogs (Rana temporaria) exposed to a viral pathogen (Ranavirus). [PDF]

, 2009
(c) 2009 Teacher et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
AA Cunningham, AA Cunningham, AL Hughes, Amber G. F. Teacher, AVS Hill, B Sammut, BC Clarke, BP Shum, D Posada, G Froeschke, GD Maniero, J Gantress, J Maynard Smith, J Robert, JM Seddon, JM Vyas, K Roelants, K Tamura, L Bernatchez, LF Jensen, M Nei, M Nonaka, M Ohtsuka, MA Beaumont, MF Flajnik, MF Flajnik, MF Flajnik, PC Doherty, PW Hedrick, R Frankham, RD Campbell, Richard A. Nichols, Robert DeSalle, S Berlin, S Conseguera, S Kumar, S Rozen, SB Piertney, T Antao, Trenton W. J. Garner, WE Briles, WF Bodmer, Y Ohta   +42 more
core   +6 more sources

Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish

Cells, 2019
Fascinating about classical major histocompatibility complex (MHC) molecules is their polymorphism. The present study is a review and discussion of the fish MHC situation. The basic pattern of MHC variation in fish is similar to mammals, with MHC class I
Takuya Yamaguchi, Johannes M. Dijkstra
doaj   +1 more source

Palladium-Induced Temporal Internalization of MHC Class I Contributes to T Cell-Mediated Antigenicity

Frontiers in Immunology, 2021
Palladium (Pd) is a widely used metal and extremely important biomaterial for the reconstruction of occlusions during dental restorations. However, metallic biomaterials can cause serious allergic reactions, such as Pd-related oral mucositis seen in ...
Koyu Ito, Takayuki Kanaseki, Serina Tokita, Serina Tokita, Toshihiko Torigoe, Noriyasu Hirasawa, Kouetsu Ogasawara   +6 more
doaj   +1 more source

A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells [PDF]

, 2007
Viral mutational escape can reduce or abrogate recognition by the T cell receptor (TCR) of virus-specific CD8+ T cells. However, very little is known about the impact of cytotoxic T lymphocyte (CTL) epitope mutations on interactions between peptide–major
Allen, R, Allen, TM, Allgaier, R, Altfeld, M, Feeney, M, Gandhi, RT, Kavanagh, DG, Lichterfeld, M, Miura, T, Moza, B, Mui, SK, Pereyra, F, Rosenberg, ES, Sivamurthy, R, Sundberg, EJ, Trocha, A, Walker, BD, Williams, KL, Yu, XG   +18 more
core   +3 more sources

Differential MHC class I expression in distinct leukocyte subsets

BMC Immunology, 2011
Background MHC class I proteins are partly responsible for shaping the magnitude and focus of the adaptive cellular immune response. In humans, conventional wisdom suggests that the HLA-A, -B, and -C alleles are equally expressed on the majority of cell ...
Broman Karl W, Kunstman Kevin J, Hawkins Oriana E, Lhost Jennifer J, Burwitz Benjamin J, Karl Julie A, Bimber Benjamin N, Lank Simon M, Wiseman Roger W, Greene Justin M, Wolinsky Steven M, Hildebrand William H, O'Connor David H   +12 more
doaj   +1 more source

EXPRESSION OF A FUNCTIONAL CHIMERIC lg-MHC CLASS II PROTEIN [PDF]

, 1992
composed of the a- and ß-chains of the MHC class I1 I-E molecule fused to antibody V regions derived from anti-human CD4 mAb MT310. Expression vectors were constructed containing the functional, rearranged gene segments coding for the V region domains of
Becker, Andrea, Karlsson, Lars, Peterson, Per A., Rieber, Ernst Peter, Riethmüller, Gert, Weiss, Elisabeth H., Weissenhorn, Winfried, Widera, Georg, Zwirner, Jörg   +8 more
core   +1 more source

The MHC Class Ia Genes in Chenfu’s Treefrog (Zhangixalus chenfui) Evolved via Gene Duplication, Recombination, and Selection

Animals, 2019
The molecular mechanisms underlying the evolution of adaptive immunity-related proteins can be deduced by a thorough examination of the major histocompatibility complex (MHC).
Hu Chen, Siqi Huang, Ye Jiang, Fuyao Han, Qingyong Ni, Yongfang Yao, Huailiang Xu, Sudhanshu Mishra, Mingwang Zhang   +8 more
doaj   +1 more source

MHC class I multimers.

Arthritis research, 2001
T lymphocytes play a key role in the immune response to both foreign and self peptide antigens, which they recognize in combination with MHC molecules. In the past it has been difficult to analyse objectively the specificity, frequency and intensity of T cell responses.
Sun, M, Bowness, P
openaire   +2 more sources