Indian Journal of Transplantation, 2023 Aim: The aim of this study was to analyze the cross-presentation of allopeptides derived from donor major histocompatibility (MHC) molecules by recipient class I MHC molecules in the context of transplantation rejection.
Suhana Koothradan, K K Elyas
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Structural analysis of the adenovirus type 2 E3/19K protein using mutagenesis and a panel of conformation-sensitive monoclonal antibodies [PDF]
, 2008 The E3/19K protein of human adenovirus type 2 (Ad2) was the first viral protein shown to interfere with antigen presentation. This 25 kDa transmembrane glycoprotein binds to major histocompatibility complex (MHC) class I molecules in the endoplasmic ...
Ahmed +62 more
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Biology, 2016 Major histocompatibility complex (MHC) molecules are key players in initiating immune responses towards invading pathogens. Both MHC class I and class II genes are present in teleosts, and, using phylogenetic clustering, sequences from both classes have ...
Unni Grimholt
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Lack of association between alopecia areata and HLA class I and II in a southeastern Brazilian population [PDF]
Anais Brasileiros de Dermatologia, 2016 : Background: Alopecia areata (AA) is a common disorder of unknown etiology that affects approximately 0.7% to 3.8% of patients among the general population. Currently, genetic and autoimmune factors are emphasized as etiopathogenic.
Ângela Marques Barbosa +7 more
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Melanosomal targeting sequences from gp100 are essential for MHC class II-restricted endogenous epitope presentation and mobilization to endosomal compartments [PDF]
, 2006 CD4+ T lymphocytes play an important role in CD8+ T cell-mediated responses against tumors. Considering that about 20% of melanomas express major histocompatibility complex (MHC) class II, it is plausible that concomitant antigenic presentation by MHC ...
Lapointe, Réjean, Lepage, Stéphanie
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A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes [PDF]
, 1989 Peptides that are antigenic for T lymphocytes are ligands for two receptors, the class I or II glycoproteins that are encoded by genes in the major histocompatibility complex, and the idiotypic / chain T-cell antigen receptor1–9. That a peptide must bind
A Sette +30 more
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Antibody-mediated rejection of arterialised venous allografts is inhibited by immunosuppression in rats. [PDF]
PLoS ONE, 2014 OBJECTIVES AND DESIGN: We determined in a rat model (1) the presence and dynamics of alloantibodies recognizing MHC complexes on quiescent Brown-Norway (BN) splenic cells in the sera of Lewis (LEW) recipients of Brown-Norway iliolumbar vein grafts under ...
Katrin Splith +11 more
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Contrasting patterns of selection between MHC I and II across populations of Humboldt and Magellanic penguins [PDF]
, 2016 Indexación: Web of ScienceThe evolutionary and adaptive potential of populations or species facing an emerging infectious disease depends on their genetic diversity in genes, such as the major histocompatibility complex (MHC). In birds, MHC class I deals
Dantas, GPM +7 more
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Immuno, 2021 MHC class I molecules display intracellular peptides on cell surfaces to enable immune surveillance under pathological conditions. The source of MHC class I antigens responsible for cancer protection is not fully understood.
Serina Tokita +2 more
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Induction of specific tolerance by intrathymic injection of recipient muscle cells transfected with donor class I major histocompatibility complex. [PDF]
, 1994 Induction of tolerance to allogeneic MHC antigens has been a goal in the field of transplantation because it would reduce or eliminate the need for generalized immunosuppression.
Geissler, Edward K. +5 more
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