Results 31 to 40 of about 534,915 (376)
The Journal of Poultry Science, 2005 The aim of this study was to determine whether the expressions of MHC class I and II in the ovarian follicles change with follicular growth and aging of birds. Theca layer of white follicles (WF), the largest and the third largest preovulatory follicles
Kalpana Subedi, Yukinori Yoshimura
doaj +1 more source
Contrasting patterns of selection between MHC I and II across populations of Humboldt and Magellanic penguins [PDF]
, 2016 Indexación: Web of ScienceThe evolutionary and adaptive potential of populations or species facing an emerging infectious disease depends on their genetic diversity in genes, such as the major histocompatibility complex (MHC). In birds, MHC class I deals
Dantas, GPM +7 more
core +1 more source
Functional consequences of the binding of MHC class ll-derived peptides to MHC class II [PDF]
International Immunology, 1996 Three MHC class II-derived synthetic peptides (I-A beta (g7)1-16, I-A beta (g7)52-77 and I-A alpha (g7)63-82YC) were analyzed for their ability to bind to syngeneic and allogeneic MHC class II molecules using a whole cell, competitive peptide binding assay.
Maryam Feili-Hariri +4 more
openaire +2 more sources
Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression [PDF]
, 1996 CIITA activates the expression of multiple genes involved in antigen presentation and it is believed to be required for both constitutive and IFN\xce\xb3-inducible expression of these genes.
Chang, C.-H. (Cheong-Hee) +4 more
core +1 more source
Induction of MHC Class I Expression by the MHC Class II Transactivator CIITA [PDF]
Immunity, 1997 Major histocompatibility complex (MHC) class I–deficient cell lines were used to demonstrate that the MHC class II transactivator (CIITA) can induce surface expression of MHC class I molecules. CIITA induces the promoter of MHC class I heavy chain genes. The site α DNA element is the target for CIITA-induced transactivation of class I.
Martin, Brian K +6 more
openaire +2 more sources
Biology, 2016 Major histocompatibility complex (MHC) molecules are key players in initiating immune responses towards invading pathogens. Both MHC class I and class II genes are present in teleosts, and, using phylogenetic clustering, sequences from both classes have ...
Unni Grimholt
doaj +1 more source
Footprints of antigen processing boost MHC class II natural ligand predictions
Genome Medicine, 2018 Major histocompatibility complex class II (MHC-II) molecules present peptide fragments to T cells for immune recognition. Current predictors for peptide to MHC-II binding are trained on binding affinity data, generated in vitro and therefore lacking ...
C. Barra +7 more
semanticscholar +1 more source
MHC class II tetramers made from isolated recombinant α and β chains refolded with affinity-tagged peptides. [PDF]
PLoS ONE, 2013 Targeting CD4+ T cells through their unique antigen-specific, MHC class II-restricted T cell receptor makes MHC class II tetramers an attractive strategy to identify, validate and manipulate these cells at the single cell level.
Peter Braendstrup +7 more
doaj +1 more source
Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80(dim), CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients [PDF]
, 1996 We have shown previously that granulocyte-macrophage colony-stimulating factor-stimulated mouse bone marrow-derived MHC class II+ dendritic cell (DC) progenitors that are deficient in cell surface expression of the costimulatory molecules B7-1 (CD8O) and
Angus W. Thomson +48 more
core +1 more source
PLoS ONE, 2017 Tumor-infiltrating lymphocytes (TILs) have been known for their strong prognostic and predictive significance in triple-negative breast cancer (TNBC). Several mechanisms for TIL influx in TNBC have been elucidated.
I. Park +9 more
semanticscholar +1 more source