Results 21 to 30 of about 4,097 (189)

Contribution of adrenergic receptors to anti-allodynic effect of mianserin in experimentally induced diabetic neuropathy model

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Our research group previously reported that mianserin has the ability to reduce diabetic neuropathic pain at doses of 30 and 45 mg/kg, comparable to a widely prescribed drug, pregabalin (10 mg/kg), used in the clinical treatment of ...
Umut Irfan Ucel, Ozgur Devrim Can, Umide Demir Ozkay   +2 more
doaj  

Beneficial effect of mianserin in experimentallyinduced chronic hyperglycemia: evidence of increased Ins1 mRNA expression

Psychiatry and Clinical Psychopharmacology, 2021
Objective: The aim of this study was investigating the potential effect of subacute mianserin administration on diabetes-induced chronic hyperglycemia and metabolic alterations.
Ozgur Devrim Can, Umide Demir Ozkay, Miris Dikmen, Umut Irfan Ucel   +3 more
doaj  

Ultraviolet spectrophotometric method for analytical determination of mianserin hydrochloride in coated tablets and comparison with LC

Brazilian Journal of Pharmaceutical Sciences, 2015
Ultraviolet spectrophotometric (UV) and Liquid Chromatographic (LC) methods for the determination of mianserin hydrochloride in pharmaceutical formulation were developed and validated. The various parameters, such as specificity, linearity, precision and
Letícia Lenz Sfair, Jeferson Scarpari Graeff, Martin Steppe, Elfrides Eva Scherman Schapoval   +3 more
doaj   +1 more source

Influence of combined treatment with mianserin and simvastatin on selected biochemical serum parameters of liver and kidney function in rats

Current Issues in Pharmacy and Medical Sciences, 2013
The aim of the present study was to assess the impact of combined 14-day treatment with mianserin (10 mg/kg) and simvastatin (1 or 10 mg/kg) on selected biochemical liver and kidney parameters in rats (AST and ALT activities and the concentrations of ...
Mariola Herbet, Monika Gawrońska-Grzywacz, Magdalena Izdebska, Ewa Jagiełło-Wójtowicz   +3 more
doaj   +1 more source

Asymptomatic syndrome of inappropriate secretion of antidiuretic hormone (SIADH) following duloxetine treatment for pain with depression: Two case reports

Neuropsychopharmacology Reports, 2022
Background Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a common side effect in patients treated with SSRIs and venlafaxine, while there is little information on SIADH in the treatment of duloxetine for pain.
Aoi Sato, Norio Yasui‐Furukori, Yumiko Oda, Misa Yang, Yudai Suzuki, Masataka Shinozaki, Taro Shimizu, Kazutaka Shimoda   +7 more
doaj   +1 more source

Role of Biogenic Amines in Oviposition by the Diamondback Moth, Plutella xylostella L

Frontiers in Physiology, 2020
Oviposition is an important reproductive behavior that is triggered by mating in insects, and biogenic amines might be involved in its regulation. The effects of biogenic amines on oviposition have only been studied in a few insect species, and the ...
Fan Li, Ke Li, Li-Juan Wu, Yong-Liang Fan, Tong-Xian Liu   +4 more
doaj   +1 more source

The Effect of Mianserin on Lifespan of Caenorhabditis elegans is Abolished by Glucose

, 2021
Background: The antidepressant mianserin has been shown to extend the lifespan of Caenorhabditis elegans (C. elegans), a well-established model organism used in aging research. The extension of lifespan in C.
Mihiri Munasinghe (9488681), Abdullah Almotayri (9937703), Jency Thomas (9495959), Markandeya Jois (9484886)   +3 more
core   +1 more source

Antidepressants of the serotonin-antagonist type increase body fat and decrease lifespan of adult Caenorhabditis elegans. [PDF]

PLoS ONE, 2008
It was recently suggested that specific antidepressants of the serotonin-antagonist type, namely mianserin and methiothepin, may exert anti-aging properties and specifically extend lifespan of the nematode C.elegans by causing a state of perceived ...
Kim Zarse, Michael Ristow
doaj   +1 more source

Comorbid epilepsy and depression—pharmacokinetic and pharmacodynamic drug interactions

Frontiers in Pharmacology, 2022
Background: Major depressive disorder may be encountered in 17% of patients with epilepsy and in patients with drug-resistant epilepsy its prevalence may reach 30%.
Barbara Miziak, Stanisław J. Czuczwar, Ryszard Pluta   +2 more
doaj   +1 more source

Stereoselective Interaction of Mianserin with 5-HT3 Receptors

, 1993
The interaction of the enantiomers of mianserin with the 5-HT3 receptor was determined. Using [3H]granisetron binding, (–)-mianserin was more potent than (+)-mianserin (pKi 8·46 and 6·95, respectively).
D R Thomas, C J Watkins, N R Newberry, M D Wood   +3 more
core   +1 more source