Results 111 to 120 of about 481,437 (386)

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

open access: yesAdvanced Science, EarlyView.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou   +18 more
wiley   +1 more source

Major Histocompatibility Complex Class I Chain-Related A (MICA) Molecules: Relevance in Solid Organ Transplantation

open access: yesFrontiers in Immunology, 2017
An ever growing number of reports on graft rejection and/or failure even with good HLA matches have highlighted an important role of non-HLA antigens in influencing allograft immunity.
A. Baranwal, N. Mehra
semanticscholar   +1 more source

GENERAL AND SPECIFIC COMBINING ABILITY OF TROPICAL MAIZE GERMPLASM

open access: yesTropical and Subtropical Agroecosystems, 2008
Eight tropical maize populations were crossed in a diallel system. Parent and their 28 crosses were evaluated for grain yield in two plantations in 2006.
Pedro Guillen de la Cruz   +6 more
doaj  

A Methodology for Deciphering the Transmembrane Resistance Variability of Supported Lipid Bilayers

open access: yesAdvanced Science, EarlyView.
This work shows that transmembrane resistance variability, due to lipid packing defects, can be quantified by analysing the dielectric properties of Supported Lipid Bilayers. The proposed methodology provides an analytical tool for optimizing SLB design with improved stability and functionality for bioelectronic and biomimetic applications. Abstract In
Aristea Pavlou   +6 more
wiley   +1 more source

Resveratrol promotes MICA/B expression and natural killer cell lysis of breast cancer cells by suppressing c-Myc/miR-17 pathway

open access: yesOncoTarget, 2017
Major histocompatibility complex class I chain-related proteins A and B (MICA and MICB) are important ligands for recognition of tumor cells by immune effector cells.
Jie Pan   +8 more
semanticscholar   +1 more source

Biodistribution and dosimetry of the PET radioligand [18F]CHDI-650 in mice for detection of mutant huntingtin aggregates

open access: yesEJNMMI Research
Background Huntington’s disease (HD) is a rare neurodegenerative disorder caused by an expansion of the CAG trinucleotide repeat in the huntingtin gene which encodes the mutant huntingtin protein (mHTT) that is associated with HD-related ...
Jordy Akkermans   +10 more
doaj   +1 more source

The building stones and slates of Killin : an investigation of stone for the built heritage [PDF]

open access: yes, 2010
The village of Killin lies in an area of dramatic landscape and mountain scenery. The use of local stone in the buildings gives a direct connection to this landscape and reflects the local geology, comprising mostly metamorphic rocks of Precambrian age
Albornoz-Parra, L.J.   +5 more
core  

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

open access: yesAdvanced Science, EarlyView.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei   +8 more
wiley   +1 more source

Disordered Glass Nanowire Substrates Produce in Vivo‐Like Astrocyte Morphology Revealed by Low‐Coherence Holotomography

open access: yesAdvanced Science, EarlyView.
Low‐coherence holotomography reveals that disordered nanowire substrates guide astrocyte morphology toward branched, in vivo–like star‐shaped morphology, emphasizing the role of biophysical cues in shaping neural cell behavior. The developed nanostructured platform offers a new route to study astrocytes for neurobiology studies. Abstract Astrocytes are
Pooja Anantha   +11 more
wiley   +1 more source

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