Results 131 to 140 of about 457,272 (378)

Combining PIM‐2 and PARP1 Inhibitors Induces MICA Expression on Multiple Myeloma Cells to Activate NK Cells through NKG2D Binding

Advanced Science, EarlyView.
The findings suggest that the combination of PIM‐2 and PARP1 inhibitors can induce MICA expression on MM cells, thereby activating NK cells through NKG2D binding. This process may restore NK cell function and serve as a potential therapeutic approach for MM patients. Abstract While immunogenic death in tumor cells activates specific anti‐tumor T cells,
Zhaoyun Liu, Wenhui Lei, Xiaohan Liu, Hui Liu, Kai Ding, Jia Song, Rong Fu   +6 more
wiley   +1 more source

GENERAL AND SPECIFIC COMBINING ABILITY OF TROPICAL MAIZE GERMPLASM

Tropical and Subtropical Agroecosystems, 2008
Eight tropical maize populations were crossed in a diallel system. Parent and their 28 crosses were evaluated for grain yield in two plantations in 2006.
Pedro Guillen de la Cruz, Efraín De La Cruz Lázaro, Guillermo Castañon Najera, Rodolfo Osorio Osorio, Nancy Patricia Brito Manzano, Alejandro Lozano del Río, Ulises López Noverola   +6 more
doaj  

Effect of Surface Roughness on Improved Lubricity under an Ironing Condition Using a Synthetic Mica-Organic Intercalation Compound

Tribology Online, 2017
It is well known that the surface roughness of metal substrates considerably influences the tribological properties of solid lubricants. In this study, the surfaces of metal substrates were modified by wet-blasting and polishing, and the lubrication ...
Kenichiro Oshita, Mutsumi Yanagi, Yasuhiro Okada, Shinobu Komiyama, Zhigang Wang   +4 more
doaj   +1 more source

Electro-optic modulator for infrared laser using gallium arsenide crystal [PDF]

, 1968
Gallium arsenide electro-optic modulator used for infrared lasers has a mica quarter-wave plate and two calcite polarizers to amplitude or phase modulate an infrared laser light source in the wavelength range from 1 to 3 microns. The large single crystal
Walsh, T. E.
core   +1 more source

Helicobacter pylori Detection Based on Synergistic Electromagnetic and Chemical Enhancement of Surface‐Enhanced Raman Scattering in 3D Hotspot‐Activated Gold Nanorods/Nano Mica Platelets/ZnO Quantum Dots

Advanced Science, EarlyView.
Gold nanorods hybridized with nano mica platelets and ZnO quantum dots are used for the rapid, sensitive, selective, and reproducible surface‐enhanced Raman scattering‐based detection of Helicobacter pylori in different scenarios. The origin of this high performance is ascribed to the synergy between the three operational enhancement mechanisms and the
Ming‐Chang Lu, Yung‐Chi Yang, Chia‐Jung Lee, Chih‐Wei Chiu   +3 more
wiley   +1 more source

Biodistribution and dosimetry of the PET radioligand [18F]CHDI-650 in mice for detection of mutant huntingtin aggregates

EJNMMI Research
Background Huntington’s disease (HD) is a rare neurodegenerative disorder caused by an expansion of the CAG trinucleotide repeat in the huntingtin gene which encodes the mutant huntingtin protein (mHTT) that is associated with HD-related ...
Jordy Akkermans, Alan Miranda, Jeroen Verhaeghe, Filipe Elvas, Franziska Zajicek, Jonathan Bard, Longbin Liu, Vinod Khetarpal, Robert Doot, Steven Staelens, Daniele Bertoglio   +10 more
doaj   +1 more source

Impact of the MICA-129Met/Val Dimorphism on NKG2D-Mediated Biological Functions and Disease Risks

Frontiers in Immunology, 2016
The major histocompatibility complex (MHC) class I chain-related A (MICA) is the most polymorphic non-classical MHC class I gene in humans. It encodes a ligand for NKG2D (NK group 2, member D), an activating natural killer (NK) receptor that is expressed
Antje Isernhagen, D. Malzahn, H. Bickeböller, R. Dressel   +3 more
semanticscholar   +1 more source

Los nevos melanocíticos premalignos quiescentes no expresan la molécula MHC class I chain-related protein A [PDF]

, 2011
The MHC class I chain-related protein A (MICA) is an inducible molecule almost not expressed by normal cells but strongly up-regulated in tumor cells. MICA-expressing cells are recognized by natural killer (NK) cells, CD8+ abTCR and gdTCR T lymphocytes ...
Allevato, Miguel Angel, Cabrera, Hugo Nestor, Fuertes, Mercedes Beatriz, Peralta, Carlos Manuel, Rossi, Lucas Ezequiel, Zwirner, Norberto Walter   +5 more
core  

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

Advanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv, Xiang Zhao, Songsong Teng, Xinmeng Jin, Ying Zhou, Yueyang Sun, Hao Pei, Zuoqin Yan, Chunhui Ma   +8 more
wiley   +1 more source

Reserva mineral de potássio em Latossolo cultivado com Pinus taeda L.

Revista Brasileira de Ciência do Solo, 2013
No Brasil, aproximadamente 1,87 milhões de hectares são plantados com as espécies de Pinus, normalmente em solos pobres quimicamente. Os objetivos deste trabalho foram estudar a mineralogia das frações areia, silte e argila e estimar a reserva mineral de
Michael Jonathan Fernandes Alves, Vander de Freitas Melo, Carlos Bruno Reissmann, Jéssica Fernandes Kaseker   +3 more
doaj   +1 more source