Results 51 to 60 of about 9,080 (185)

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson, Catalina Silva‐Hirschberg, Liliana Freeland, Kristen L. Chen, Nagore I. Marín‐Ramos, Axel H. Schönthal, Thomas C. Chen   +6 more
wiley   +1 more source

Varieties of Hairless-Like Mutant Mice

Journal of Investigative Dermatology, 1971
The use of animal models as experimental tools is being utilized more frequently in all areas of investigation including dermatologic research. When the animal model is represented by a genetic mutation, care must be exercised so as not to confuse mutant animals that look alike but are genetically and morphologically unrelated.
openaire   +2 more sources

Transcriptional benchmark dose modeling of ultraviolet radiation‐induced genomic activation in mouse skin

Photochemistry and Photobiology, EarlyView.
Exposure to ultraviolet radiation (UV‐R) from tanning equipment increases skin cancer risk through molecular changes, but genomic thresholds remain unclear. Using mice, we examined dose‐ and time‐dependent gene expression after erythemally‐weighted UV‐R doses (0–40 mJ/cm2).
Sami S. Qutob, Samantha P. M. Roesch, Sandy Smiley, Pascale V. Bellier, Andrew Williams, Kate B. Cook, Matthew J. Meier, Andrea Rowan‐Carroll, Carole L. Yauk, James P. McNamee, Vinita Chauhan   +10 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Development of Numerous Nerve Fibers in the Epidermis of Hairless Mice With Atopic Dermatitis-Like Pruritic Skin Inflammation

Journal of Pharmacological Sciences, 2007
Itching is the most important symptom in atopic dermatitis because the persistent scratching in response to itching aggravates the disease. However, the etiologic mechanisms of itching in atopic dermatitis remain uncertain.
Masanori Fujii, Keisuke Akita, Nobuaki Mizutani, Takeshi Nabe, Shigekatsu Kohno   +4 more
doaj   +1 more source

Chemotherapy of Cutaneous Herpesvirus Infection of Hairless Mice

Journal of Investigative Dermatology, 1973
A hairless mouse-herpes simplex virus system was used to evaluate the efficacy of a variety of antiviral compounds, inducers of interferon (IF) and exogenous IF. In this model herpes simplex virus produces a local lesion which can be readily examined. Of the DNA virus inhibitors studied, 9-β-D-arabinofuranosyladenine delayed the onset and reduced the ...
Lieberman, M, Schafer, T W, Came, P E
openaire   +2 more sources

Postbiotics: An Overview and Recommendations for Improved Reporting

Molecular Nutrition &Food Research, Volume 70, Issue 14, 29 July 2026.
Human clinical trials of postbiotics and corresponding preclinical evidence were evaluated. Key reporting gaps identified included inconsistent terminology, incomplete inactivation method reporting, variable dosing information, insufficient quality‐control data, and inadequate taxonomic characterization.
Mehreen Anjum, Arthur C. Ouwehand
wiley   +1 more source

Simple generation of hairless mice for in vivo imaging.

Experimental animals, 2017
The in vivo imaging of mice makes it possible to analyze disease progress non-invasively through reporter gene expression. As the removal of hair improves the accuracy of in vivo imaging, gene-modified mice with a reporter gene are often crossed with Hos:HR-1 mutant mice homozygous for the spontaneous Hrhr mutation that exhibit a hair loss phenotype ...
Hoshino, Yoshikazu, Mizuno, Seiya, Kato, Kanako, Mizuno-Iijima, Saori, Tanimoto, Yoko, Ishida, Miyuki, Kajiwara, Noriko, Sakasai, Tomoki, Miwa, Yoshihiro, Takahashi, Satoru, Yagami, Ken-ichi, Sugiyama, Fumihiro   +11 more
openaire   +2 more sources

Effects of Milk Protein Hydrolysates on Skin Quality and Advanced Glycation End Products in Women With Perceived Skin Dullness: Two 8‐Week Randomized Controlled Trials

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Milk protein hydrolysates have been suggested to exert protective effects against skin aging; however, clinical evidence remains limited. Aims This pilot study evaluated the effects of casein hydrolysate MMP1C and whey protein hydrolysate MMP2W on skin condition in healthy Japanese women.
Sayuri Arai, Naoki Yuda, Masaki Kurimoto, Ryota Suzuki, Hajime Nakada, Hiroshi Ochi, Miyuki Tanaka, Atsushi Nakajima, Yuki Yamamoto, Masatoshi Jinnin   +9 more
wiley   +1 more source

Don't Sweat It: Cannabinoid CB1 Receptors Reduce Sweating in a Mouse Model

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
A new galvanic skin response‐based approach offers a simple method for measuring sweating in the paws of mice. This method is used to demonstrate that cannabinoid CB1 receptors reduce baseline sweating in mice, likely via inhibition of sympathetic acetylcholine release via axonal CB1 receptors.
Natalia Murataeva, Joseph Youkilis, Yogith Rao, Alex Straiker   +3 more
wiley   +1 more source