Adult vitamin D deficiency leads to behavioural and brain neurochemical alterations in C57BL/6J and BALB/c mice [PDF]
, 2013 Epidemiological evidence suggests that low levels of vitamin D may predispose people to develop depression and cognitive impairment. While rodent studies have demonstrated that prenatal vitamin D deficiency is associated with altered brain development ...
Burne, Thomas H. J. +5 more
core +1 more source
Repurposing the Antidepressant Sertraline: A Systematic Scoping Review of Its Anticancer Mechanisms
Pharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.A multi‐targeted antidepressant with strong preclinical anticancer activity, sertraline represents a candidate for therapeutic repurposing. ABSTRACT Drug repurposing offers a cost‐effective and time‐efficient strategy for identifying new cancer therapies. Sertraline, a widely prescribed selective serotonin reuptake inhibitor (SSRI), has shown promising
Ciara B. Blum +4 more
wiley +1 more source
Differential disease restriction of Moloney and Friend murine leukemia viruses by the mouse Rmcf gene is governed by the viral long terminal repeat. [PDF]
, 1991 Neonatal CxD2 (Rmcfr) and Balb/c (Rmcfs) mice inoculated with Moloney murine leukemia virus (M-MuLV) exhibited approximately equivalent time course and pathology for disease.
Brightman, BK, Fan, H, Li, QX, Trepp, DJ
core
Immunology &Cell Biology, Volume 103, Issue 9, Page 825-843, October 2025.Therapeutic cancer vaccines require CD8+ T‐cell activation for efficacy. This response can be enhanced by rationally designing polymeric nanoparticle adjuvants. The importance of antigen location for the adjuvanticity of polymeric nanoparticles has not been fully resolved.
Jorge Huete‐Carrasco +6 more
wiley +1 more source
Effect of partial pancreatectomy on diabetic status in BALB/c mice. [PDF]
, 1999 Pancreatic regeneration after pancreatectomy has been well documented in animal models. However, the phenomenon of pancreatic regeneration in diabetes has not been exploited as yet.
Bhonde, RR, Hardikar, AA, Karandikar, MS
core +1 more source
Natural Cytotoxicity of NC-2(+) Cells Against the Growth and Metastasis of WEHI-164 Fibrosarcoma [PDF]
, 2011 We have previously reported a new receptor (NC-2) for natural cytotoxicity (NC) on murine leucocytes, identified by monoclonal antibody D9 (mAb D9). Pretreatment of mouse spleen cells with different concentrations of mAb D9 in vitro blocked NC against ...
Burton, R.C. +4 more
core +1 more source
An Examination of Heterosis in Crosses of Certain Inbred Strains of Mice [PDF]
, 1962 Author Institution: Department of Dairy Science, The Ohio State University, and Battelle Memorial Institute, Columbus ...
Cohen, Carl +2 more
core
Evaluation of an outbred mouse model for Francisella tularensis vaccine development and testing.
PLoS ONE, 2018 Francisella tularensis (Ft) is a biothreat agent for which there is no FDA-approved human vaccine. Currently, there are substantial efforts underway to develop both vaccines and the tools to assess these vaccines.
Raju Sunagar +5 more
doaj +1 more source
Genetic background strongly influences the bone phenotype of P2X7 receptor knockout mice [PDF]
, 2012 The purinergic P2X7 receptor is expressed by bone cells and has been shown to be important in both bone formation and bone resorption. In this study we investigated the importance of the genetic background of the mouse strains on which the P2X7 knock-out
Beck Jensen, J. E. +8 more
core +3 more sources
Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. [PDF]
, 1994 Leishmania major are intramacrophage parasites whose eradication requires the induction of T helper 1 (Th1) effector cells capable of activating macrophages to a microbicidal state.
Locksley, RM +4 more
core +1 more source