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[Biotransformation of mexidol in inbred BALB/C and C57BL/6 mice].

Eksperimental'naia i klinicheskaia farmakologiia, 2005
The pharmacokinetics and biotransformation of mexidol was studied in BALB/C and C57BL/6 mice. The blood plasma contains dealkylated metabolites, and the urine contains glucuronoconjugated derivatives of the drug. The process of glucuronoconjugation more intensively proceeds in C57BL/6 mice than in BALB/C mice.
S B, Seredenin   +5 more
openaire   +1 more source

Antigenic differences between male and female mice of the inbred C57BL line

Bulletin of Experimental Biology and Medicine, 1963
A method of anaphylaxis with desensitization was used to show on guinea pigs the presence of sex-linked antigens in the kidney and liver tissues of male mice (C57BL inbred strain). In the majority of the guinea pigs there occurred anaphylactic shock symptoms in response to the injection of the antigen of male mice.
openaire   +1 more source

Ethanol Teratogenesis in Selectively Bred Long‐Sleep and Short‐Sleep Mice: A Comparison to Inbred C57BL/6J Mice

Alcoholism: Clinical and Experimental Research, 1989
Sensitivity to alcohol may influence the severity of ethanol teratogenesis. To examine this hypothesis, the teratogenic effects of ethanol were compared in Long‐Sleep (LS) and Short‐Sleep (SS) mice, selectively bred for differences in ethanol‐induced narcosis.
D M, Gilliam   +3 more
openaire   +2 more sources

Genetic analysis of the mandible morphology in DDD.Cg-$$A^{y}$$/Sgn and C57BL/6J inbred mice

Journal of Genetics, 2019
Quantitative trait loci (QTL) mapping analysis was performed for the mandible morphology in DDD.Cg-Ay/Sgn and C57BL/6J inbred mice. The size and shape of the mandible was analysed by landmark-based geometric morphometrics as the centroid size and principal components (PCs), respectively.
openaire   +2 more sources

Genotypic differences in mesolimbic enkephalin gene expression in DBA/2J and C57BL/6J inbred mice

European Journal of Pharmacology, 1996
The DBA/2J and C57BL/6J (herein referred to as DBA and C57) inbred mouse strains exhibit low and high predispositions for voluntary ethanol consumption, respectively, but the neurobiological basis underlying this differential drug vulnerability remains poorly understood. Comparison of endogenous brain proenkephalin gene expression showed the C57 mouse,
G Y, Ng, B F, O'Dowd, S R, George
openaire   +2 more sources

[The determination of the oxidation phenotype in inbred C57Bl/6 and BALB/c mice].

Biulleten' eksperimental'noi biologii i meditsiny, 1991
Antipyrine oxidation was studied in C57BL/6 and BALB/c inbred mice. It was found that C57BL/6 are weak oxidant but BALB/c are strong oxidants of antipyrine. Animals F1 hybrids inherited the high capacity of antipyrine oxidation.
S B, Seredenin   +3 more
openaire   +1 more source

Complete mitochondrial genome sequence and mutations of the rhinosinusitis model inbred C57BL/6 mice strain

Mitochondrial DNA Part A, 2015
In the present work, we undertook the complete mitochondrial genome sequencing of an important rhinosinusitis model inbred rat strain for the first time. The total length of the mitogenome was 16,308 bp. It harbored 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes, and 1 non-coding control region (D-loop region).
Yizhou, Qiu   +3 more
openaire   +2 more sources

Neuroanatomy of cerebellum and olfactory bulb in a substrain of C57BL/6J inbred mice carrying a spontaneous mutation

Physiology & Behavior, 2001
Mice of the inbred C57BL/6JNmg substrain carry a mutation decreasing the size of the zinc-rich hippocampal intra- and infrapyramidal mossy fibre (IIPMF) terminal fields. In the present experiment, it was investigated whether this neurological mutation has also effects on other characteristics of the brain. No morphological differences were found in two
J, Pager   +4 more
openaire   +2 more sources

Quantitative trait loci that control body weight in DDD/Sgn and C57BL/6J inbred mice

Mammalian Genome, 2016
Inbred DDD/Sgn mice are heavier than inbred C57BL/6J mice. In the present study, we performed quantitative trait loci (QTL) mapping for body weight using R/qtl in reciprocal F2 male populations between the two strains. We identified four significant QTL on Chrs 1, 2, 5, and 17 (proximal region).
Jun-Ichi, Suto, Misaki, Kojima
openaire   +2 more sources

Complete mitochondrial genome sequence and mutations of the Glioma model inbred C57BL/6 mice strain

Mitochondrial DNA Part A, 2014
In the present work we undertook the complete mitochondrial genome sequencing of an important glioma model inbred rat strain for the first time. The total length of the mitogenome was 16,308 bp. It harbored 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes and 1 non-coding control region (D-loop region).
Hong-Zhi, Gao   +5 more
openaire   +2 more sources

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