Results 171 to 180 of about 209,389 (213)
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Brain Research, 1999
The inbred 129 substrains have been characterized as poor learners that display hypoplasia of the corpus callosum. However, they are used extensively as a source of embryonic stem (ES) cells for creating mice carrying altered copies of a targeted gene ('knockout mice'). The present research investigated callosal agenesis and behavior in the 129/SvEvTac
S A, Balogh +3 more
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The inbred 129 substrains have been characterized as poor learners that display hypoplasia of the corpus callosum. However, they are used extensively as a source of embryonic stem (ES) cells for creating mice carrying altered copies of a targeted gene ('knockout mice'). The present research investigated callosal agenesis and behavior in the 129/SvEvTac
S A, Balogh +3 more
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Behavior Genetics, 1994
Exploratory behaviors as well as pharmacological actions of gamma-aminobutyric acidA (GABAA)/benzodiazepine receptor agonists and inverse agonists were characterized in C57BL/6J and A/J strains of mice. C57BL/6J mice displayed higher levels of exploratory behavior than A/J mice in the light in equilibrium with dark exploration model of anxiety and in ...
C, Mathis, S M, Paul, J N, Crawley
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Exploratory behaviors as well as pharmacological actions of gamma-aminobutyric acidA (GABAA)/benzodiazepine receptor agonists and inverse agonists were characterized in C57BL/6J and A/J strains of mice. C57BL/6J mice displayed higher levels of exploratory behavior than A/J mice in the light in equilibrium with dark exploration model of anxiety and in ...
C, Mathis, S M, Paul, J N, Crawley
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PCBs and PBBs: Biologic and toxic effects on C57BL/6J and DBA/2J inbred mice
Toxicology, 1984Treatment of genetically inbred "responsive" C57BL/6J and "non-responsive" DBA/2J mice with Aroclor 1254 or fireMaster BP-6 resulted in the induction of hepatic microsomal benzo[a]pyrene hydroxylase only in the former mouse strain and aminopyrine N-demethylase in both strains of mice.
Larry W Robertson +2 more
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Alveolar Process Anabolic Activity in C3H/HeJ and C57BL/6J Inbred Mice
Journal of Periodontology, 2008Background: The purpose of this study was to characterize bone activity of the alveolar process in C3H/HeJ (C3H) and C57BL/6J (B6) inbred mice. Based on observations in other animal species, we hypothesized that the bone‐formation rate/bone surface (BFR/BS) is greater in the alveolar process compared to the body of the mandible and that the bone ...
Isaac F, Meta +3 more
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Characterization of cortical spindles in DBA/2 and C57BL/6 inbred mice
Brain Research Bulletin, 1984Continuous twenty-four hour EEG recordings were conducted on freely-moving DBA/2 and C57BL/6 inbred mice. No brief spindle episodes (BSEs: 6-7 cps, 1-5 sec duration, high amplitude spindle bursts) were seen in the waking EEG of C57BL/6 mice. BSEs were a conspicuous element of the EEG during active waking (AW) and quiet waking (QW) in DBA/2 mice.
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American Journal of Physiology-Heart and Circulatory Physiology
We observed major vascular physiological differences between C57BL/6J and C57BL/6N mice, indicating C57BL/6N mice have greater vascular function. However, in comparison to either C57BL/6 substrain, outbred, genetically diverse UM-HET3 mice have a greater vascular function characterized by lower aortic stiffness and greater endothelial-dependent ...
Mostafa Sabouri +6 more
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We observed major vascular physiological differences between C57BL/6J and C57BL/6N mice, indicating C57BL/6N mice have greater vascular function. However, in comparison to either C57BL/6 substrain, outbred, genetically diverse UM-HET3 mice have a greater vascular function characterized by lower aortic stiffness and greater endothelial-dependent ...
Mostafa Sabouri +6 more
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Behavior Genetics, 1998
The role of genotype in susceptibility to the behavioral actions of benzodiazepines is not well characterized. To develop a model for such studies, we have characterized the anxiolytic and sedative activities of diazepam in C57BL/6J and A/J inbred mice. C57BL/6J mice were more responsive than A/J mice to diazepam-induced anxiolytic-like activity in the
K M, Garrett +4 more
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The role of genotype in susceptibility to the behavioral actions of benzodiazepines is not well characterized. To develop a model for such studies, we have characterized the anxiolytic and sedative activities of diazepam in C57BL/6J and A/J inbred mice. C57BL/6J mice were more responsive than A/J mice to diazepam-induced anxiolytic-like activity in the
K M, Garrett +4 more
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Large deletion on the Y-chromosome long arm (Yq) of C57BL/6JBomTac inbred mice
Mammalian Genome, 2016The Y-chromosome of mice has a crucial role in sex determination, gender ratio equilibrium as well as male fertility, and is moreover involved in behavioral, immunological, and cardiovascular traits. During routine short tandem repeat genotyping of C57BL/6 substrains, a unique deletion on the Y-chromosome long arm of males from the commercially ...
Melina, Fischer +3 more
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Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice
Mammalian Genome, 1999Genetic analyses for loci regulating bone mineral density have been conducted in a cohort of F(2) mice derived from intercross matings of (C57BL/6J x CAST/EiJ)F(1) parents. Femurs were isolated from 714 4-month-old females when peak adult bone density had been achieved.
Beamer, W G +6 more
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Age-related changes in the motricity of the inbred mice strains 129/sv and C57BL/6j
Behavioural Brain Research, 2007The development of motor skills was studied at different stages in the life of the mouse, focusing on three key aspects of motor development: early rhythmic motor activities prior to the acquisition of quadruped locomotion, motor skills in young adults, and the effect of aging on motor skills.
Najet, Serradj, Marc, Jamon
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