Results 171 to 180 of about 1,442,388 (221)

Identification of vacuolar autophagic aggregates in the skeletal muscles of inbred C57BL/6NCrl mice

Laboratory Animals, 2023
A comprehensive pathological analysis of inbred strains is essential to define strain-specific spontaneous lesions and to understand whether a specific phenotype results from experimental intervention or reflects a naturally occurring disease. This study aimed to report and describe a novel condition affecting the skeletal muscles of an inbred C57BL ...
De Biase D., Pagano T. B., Malanga D., Russo V., Piegari G., d'Aquino I., Iovane V., Scarfo M., Papparella S., Wojcik S., Paciello O.   +10 more
  +7 more sources

Bone Brittleness Varies with Genetic Background in A/J and C57BL/6J Inbred Mice [PDF]

Journal of Bone and Mineral Research, 2001
Abstract The contribution of genetic and environmental factors to variations in bone quality are understood poorly. We tested whether bone brittleness varies with genetic background using the A/J and C57BL/6J inbred mouse strains.
Karl J Jepsen, Joseph H Nadeau, Matthew Warman   +2 more
exaly   +3 more sources

Behavioural and neuroanatomical divergence between two sublines of C57BL/6J inbred mice

Behavioural Brain Research, 1991
Male mice of strains C57BL/6J and DBA/2J differ reproducibly in a number of behaviours displayed in an open-field. In particular, C57BL/6J mice show a higher rearing-up frequency than do DBA/2J animals. Recently, a marked drop occurred in the frequency with which this behaviour is displayed by the C57BL/6J//Nmg (N) subline, that has been separated from
Wim Crusio, H Schwegler, J H F van Abeelen   +2 more
exaly   +3 more sources

Maternal Behavior in Female C57BL/6J and DBA/2J Inbred Mice

Physiology and Behavior, 1999
Inbred strains of mice exhibit different patterns of maternal behavior, providing material for studies of genetic influences on the expression of maternal behavior. Beginning 1 day after birth, maternal behavior was recorded daily for 14 days in the first and second litters of C57BL/6J (B6) and DBA/2J (D2) mothers.
Richard E Brown, Paul E Neumann
exaly   +3 more sources

Discriminative Stimulus Effects of Ethanol in C57BL/6J and DBA/2J Inbred Mice

Alcoholism: Clinical and Experimental Research, 2002
Background: Two of the most widely used mouse strains for studying the behavioral effects of ethanol are C57BL/6J (B6) and DBA/2J (D2) mice. These strains exhibit marked differences in behavioral and physiological responses to ethanol. The subjective discriminative stimulus effects of ethanol may play a role in ethanol abuse, but the discriminative ...
Kathleen A Grant, Keith L. Shelton
exaly   +3 more sources

Genetic control of hepatocarcinogenesis in C57BL/6J and C3H/HeJ inbred mice

Carcinogenesis, 1986
Treatment of newborn male C3H/HeJ mice with N,N-diethyl-nitrosamine (DEN) or N-ethyl-N-nitrosourea (ENU) resulted in the induction of hepatocellular adenomas and carcinomas with a mean number of tumors per animal that was approximately 20- to 50-fold higher than that for similarly treated C57BL/6J male mice.
N R, Drinkwater, J J, Ginsler
openaire   +2 more sources

A behavioral and neuroanatomical assessment of an inbred substrain of 129 mice with behavioral comparisons to C57BL/6J mice

Brain Research, 1999
The inbred 129 substrains have been characterized as poor learners that display hypoplasia of the corpus callosum. However, they are used extensively as a source of embryonic stem (ES) cells for creating mice carrying altered copies of a targeted gene ('knockout mice'). The present research investigated callosal agenesis and behavior in the 129/SvEvTac
S A, Balogh, C S, McDowell, A J, Stavnezer, V H, Denenberg   +3 more
openaire   +2 more sources

PCBs and PBBs: Biologic and toxic effects on C57BL/6J and DBA/2J inbred mice

Toxicology, 1984
Treatment of genetically inbred "responsive" C57BL/6J and "non-responsive" DBA/2J mice with Aroclor 1254 or fireMaster BP-6 resulted in the induction of hepatic microsomal benzo[a]pyrene hydroxylase only in the former mouse strain and aminopyrine N-demethylase in both strains of mice.
Stephen Safe, Larry W Robertson, A Parkinson   +2 more
exaly   +3 more sources

Alveolar Process Anabolic Activity in C3H/HeJ and C57BL/6J Inbred Mice

Journal of Periodontology, 2008
Background: The purpose of this study was to characterize bone activity of the alveolar process in C3H/HeJ (C3H) and C57BL/6J (B6) inbred mice. Based on observations in other animal species, we hypothesized that the bone‐formation rate/bone surface (BFR/BS) is greater in the alveolar process compared to the body of the mandible and that the bone ...
Isaac F, Meta, Soledad A, Fernandez, Parul, Gulati, Sarandeep S, Huja   +3 more
openaire   +2 more sources