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Genetic analysis of cerebellar folial pattern in crosses of C57BL/6J and DBA/2J inbred mice
Brain Research, 1993Variation in the cerebellar folial pattern of mice is influenced by genetic elements [Inouye, M. and Oda, S., J. Comp. Neurol., 190 (1980) 357-362]. In crosses of C57BL/6J and DBA/2J inbred mice, the presence or absence of a specific fissure, the intraculminate fissure, is largely determined by a single genetic locus (Cfp-1), which is located on distal
Gary G. Mueller +3 more
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Quantitative trait loci that control body weight in DDD/Sgn and C57BL/6J inbred mice
Mammalian Genome, 2016Inbred DDD/Sgn mice are heavier than inbred C57BL/6J mice. In the present study, we performed quantitative trait loci (QTL) mapping for body weight using R/qtl in reciprocal F2 male populations between the two strains. We identified four significant QTL on Chrs 1, 2, 5, and 17 (proximal region).
Misaki Kojima, Jun-ichi Suto
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Genotypic differences in mesolimbic enkephalin gene expression in DBA/2J and C57BL/6J inbred mice
European Journal of Pharmacology, 1996The DBA/2J and C57BL/6J (herein referred to as DBA and C57) inbred mouse strains exhibit low and high predispositions for voluntary ethanol consumption, respectively, but the neurobiological basis underlying this differential drug vulnerability remains poorly understood. Comparison of endogenous brain proenkephalin gene expression showed the C57 mouse,
Gordon Y.K. Ng +2 more
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Complete mitochondrial genome sequence and mutations of the Glioma model inbred C57BL/6 mice strain
Mitochondrial DNA Part A, 2014In the present work we undertook the complete mitochondrial genome sequencing of an important glioma model inbred rat strain for the first time. The total length of the mitogenome was 16,308 bp. It harbored 13 protein-coding genes, 2 ribosomal RNA genes, 22 transfer RNA genes and 1 non-coding control region (D-loop region).
Weipeng Hu +5 more
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American Journal of Tropical Medicine and Hygiene, 1980
Schistosoma mansoni infections of CBA/J and C57BL/6 mice provided the hosts with partial protection against reinfection by S. mansoni cercariae. The level of protection, assayed by perfusion 21-25 days after challenge, varied over the course of infection.
D. Colley, G. L. Freeman
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Schistosoma mansoni infections of CBA/J and C57BL/6 mice provided the hosts with partial protection against reinfection by S. mansoni cercariae. The level of protection, assayed by perfusion 21-25 days after challenge, varied over the course of infection.
D. Colley, G. L. Freeman
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The Journal of Pharmacology and Experimental Therapeutics, 2005
Neurosteroids represent a class of endogenous compounds that exert rapid, nongenomic effects through neurotransmitter receptor systems such as GABA(A). Two neurosteroids, allopregnanolone (3alpha-hydroxy-5alpha-pregnan-20-one) and pregnanolone (3alpha-hydroxy-5beta-pregnan-20-one), possess anxiolytic and sedative properties and show substitution for ...
Robert H. Purdy +4 more
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Neurosteroids represent a class of endogenous compounds that exert rapid, nongenomic effects through neurotransmitter receptor systems such as GABA(A). Two neurosteroids, allopregnanolone (3alpha-hydroxy-5alpha-pregnan-20-one) and pregnanolone (3alpha-hydroxy-5beta-pregnan-20-one), possess anxiolytic and sedative properties and show substitution for ...
Robert H. Purdy +4 more
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Clinical Neuropharmacology, 1992
1. The influence of dexamethasone on morphine analgesia in three different strains of mice (Swiss, DBA/2J and C57BL/6) was studied by using the tail flick test. 2. I.c.v. as well as i.p. injections of dexamethasone did not modify nociceptive response in all strains. 3. I.c.v.
Ludovico Sorrentino +4 more
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1. The influence of dexamethasone on morphine analgesia in three different strains of mice (Swiss, DBA/2J and C57BL/6) was studied by using the tail flick test. 2. I.c.v. as well as i.p. injections of dexamethasone did not modify nociceptive response in all strains. 3. I.c.v.
Ludovico Sorrentino +4 more
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Cocaine Reward and Locomotor Activity in C57BL/6J and 129/SvJ Inbred Mice and Their F1 Cross
Pharmacology Biochemistry and Behavior, 1997Large individual differences exist among mice in their behavioral responses to drugs of abuse, and many of these differences have a substantial genetic basis. The creation of new animal models using recombinant DNA technology has provided new genetic tools for assessing the role of specific candidate genes in drug response.
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