Frontiers in Cellular and Infection Microbiology, 2021 Mycoplasma pneumoniae (Mp) is a highly contagious respiratory pathogen responsible for human community-acquired pneumonia. The number of antibiotic-resistant Mp strains is increasing; therefore, to develop novel therapeutics, it is crucial to precisely ...
Shigeyuki Tamiya +11 more
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Differential expression of chemokine and matrix re-modelling genes is associated with contrasting schistosome-induced hepatopathology in murine models. [PDF]
PLoS Neglected Tropical Diseases, 2011 The pathological outcomes of schistosomiasis are largely dependent on the molecular and cellular mechanisms of the host immune response. In this study, we investigated the contribution of variations in host gene expression to the contrasting hepatic ...
Carly R Perry +5 more
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Susceptibility to SARS-CoV-2 Virus Variants of Concern in Mouse Models
Проблемы особо опасных инфекций, 2022 The aim of the research was to assess the susceptibility of mice of different lines to newly emerging variants of SARS-CoV-2.Materials and methods. The SARS-CoV-2 virus strains belonging to variants of concern (VOC) circulating in the territory of the ...
A. V. Shipovalov +9 more
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Contrasting characteristic behaviours among common laboratory mouse strains [PDF]
Royal Society Open Science, 2019 Mice are widely used to model wide-ranging human neurological disorders, from development to degenerative pathophysiology. Behavioural and molecular characteristics of these mouse models are influenced by the genetic background of each strain.
Razia Sultana +2 more
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Mate genetic similarity affects mating behaviour but not maternal investment in mice
Scientific Reports, 2023 Maternal investment can affect the survival and development of offspring. Here we experimentally investigated in mice, whether females alter implantation rates and pup survival after embryo transfer depending on the genetic similarity with their ...
Kerstin E. Auer +4 more
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Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology. [PDF]
PLoS ONE, 2014 The female lower genital tract is constantly exposed to microbial infection, some of which can ascend to and cause pathology such as hydrosalpinx in the upper genital tract, which can affect fertility.
Jianlin Chen +9 more
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Frontiers in Aging Neuroscience, 2022 Age-related hearing loss (ARHL) is a major hearing impairment characterized by pathological changes in both the peripheral and central auditory systems.
Benjamin J. Seicol +4 more
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Cellular Physiology and Biochemistry, 2018 Background/Aims: Our laboratory discovered a Kunming mouse with enormous electroretinogram (ERG) defects. Its auditory brainstem response (ABR) threshold was significantly elevated and closely resembled the features of Usher syndrome (USH).
Weiming Yan +11 more
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Site and strain-specific variation in gut microbiota profiles and metabolism in experimental mice. [PDF]
PLoS ONE, 2010 The gastrointestinal tract microbiota (GTM) of mammals is a complex microbial consortium, the composition and activities of which influences mucosal development, immunity, nutrition and drug metabolism.
Melissa K Friswell +6 more
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Roles of the espin actin-bundling proteins in the morphogenesis and stabilization of hair cell stereocilia revealed in CBA/CaJ congenic jerker mice. [PDF]
PLoS Genetics, 2011 Hearing and vestibular function depend on mechanosensory staircase collections of hair cell stereocilia, which are produced from microvillus-like precursors as their parallel actin bundle scaffolds increase in diameter and elongate or shorten.
Gabriella Sekerková +2 more
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