Results 131 to 140 of about 145,801 (250)

Digit ratio (2Dratio4D) differences between 20 strains of inbred mice.

PLoS ONE, 2009
The second to fourth digit ratio (2Dratio4D) is sexually differentiated in a variety of species, including humans, rats, birds, and lizards. In humans, this ratio tends to be lower in males than in females.
Reginia H Y Yan, Mark Bunning, Douglas Wahlsten, Peter L Hurd   +3 more
doaj   +1 more source

Genetics of MuBl and of a complement defect in inbred strains of mice

Genetical Research, 1966
A mouse antigen, MuB1, has been shown by the study of backcrosses to be inherited in a unifactorial dominant manner. Its inheritance is not linked with gamma globulin allotypes, but has been shown to be linked with the presence of the haemolytic complement system.
Cinader, B, Dubiski, S, Wardlaw, A C
openaire   +3 more sources

A Candidate Subspecies Discrimination System Involving a Vomeronasal Receptor Gene with Different Alleles Fixed in \u3ci\u3eM. m. domesticus\u3c/i\u3e and \u3ci\u3eM. m. musculus\u3c/i\u3e [PDF]

, 2010
Assortative mating, a potentially efficient prezygotic reproductive barrier, may prevent loss of genetic potential by avoiding the production of unfit hybrids (i.e., because of hybrid infertility or hybrid breakdown) that occur at regions of secondary ...
Karn, Robert C., Laukaitis, Christina M., Young, Janet M.   +2 more
core   +1 more source

Targeting IGF1‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging

Aging Cell, EarlyView.
Age‐related increases in IGF‐1 expression in the skin accelerate stem cell exhaustion and senescence by impairing SIRT1 function, ultimately driving hair follicle aging. Conversely, activating SIRT1, clearing senescent cells, or adopting dietary restriction can mitigate excessive IGF‐1 signaling and provide a promising strategy to rejuvenate hair ...
Yang Wang, Jian Yang, Yue Luo, Zhiqiang Zhao, Yawen Yuan, Juan Li, Yang Liu, Yong Yi, Xiaoke Xu, Yuankunyu Lan, Juan Zou, Qintong Li, Liang Wang, Yang Pan, Yuanhan Yang, Muzhao Xiong, Min Wu, Jinsong Li, Weiyuxin Li, Yujun Zhang, Yang Cao, Yi Zhu, Zhi‐Xiong Jim Xiao   +22 more
wiley   +1 more source

Species differences in comorbid alcohol use disorder and major depressive disorder: A narrative review

Alcohol, Clinical and Experimental Research, EarlyView.
In this narrative review, we identify barriers to the translation of preclinical comorbidity models of alcohol use disorder and depressive disorders, including temporal and pharmacological discrepancies. In humans, depression is high during and immediately after the cessation of drinking and usually remits subsequently, while in animals it seems to ...
Garrett A. Winkler, Nicholas J. Grahame
wiley   +1 more source

Strain differences in seizure-induced cell death following pilocarpine-induced status epilepticus

Neurobiology of Disease, 2012
Mouse strains differ from one another in their susceptibility to seizure-induced excitotoxic cell death. Previously, we have demonstrated that mature inbred strains of mice show remarkable genetic differences in susceptibility to the neuropathological ...
P. Elyse Schauwecker
doaj  

Loss of vimentin intermediate filaments decreases peri-nuclear stiffness and enhances cell motility through confined spaces [PDF]

arXiv, 2018
The migration of cells through tight constricting spaces or along fibrous tracks in tissues is important for biological processes, such as embryogenesis, wound healing, and cancer metastasis, and depends on the mechanical properties of the cytoskeleton. Migratory cells often express and upregulate the intermediate filament protein vimentin.
arxiv  

Phenotype and gene signature of testicular tumors in 129.MOLF‐Chr19 mice resemble human teratomas

Andrology, EarlyView.
Abstract Background Testicular germ cell tumor (TGCT) is the most common type of tumor in young men. Type II germ cell tumors including postpubertal‐type teratomas are derived from the germ cell neoplasia in situ (GCNIS), whereas prepubertal‐type teratomas arise independently of the GCNIS.
Fabian A. Gayer, Lucas Klaus, Sybille D. Reichardt, Alexander Fichtner, Holger M. Reichardt   +4 more
wiley   +1 more source

The Relationship Between the Murine Primary Immune Response to Sheep Red Blood Cells & Heterosis [PDF]

, 1989
Two inbred strains of mice, BALB/c and C57BL, were crossbred to produce Fl hybrids. This breeding scheme ensured a high degree of genetic heterozygosity as exemplified by the fact that the average weight of the Fl hybrids at 10 weeks of age was 10.1 ...
Gailor, Russell
core   +1 more source

Ascorbic acid 2‐glucoside improves survival, quality, and fertility of frozen‐thawed C57Bl/6J and C57Bl/6N mouse spermatozoa

Andrology, EarlyView.
Abstract Background Ascorbic acid 2‐glucoside (AA2G) is a stabilized form of ascorbic acid and a potent antioxidant. Ascorbic acid is present in the testes and epididymis and helps maintain the physiological integrity of reproductive organs. Its properties have been utilized to protect spermatozoa of different species from oxidative stress.
Marcello Raspa, Renata Paoletti, Ferdinando Scavizzi   +2 more
wiley   +1 more source