BACKGROUND: Noninvasive intraocular pressure (IOP) measurement in mice is critically important for understanding the pathophysiology of glaucoma. Rebound tonometry is one of the methods that can be used for obtaining such measurements.
Nissirios, Nicholas +4 more
core +1 more source
“Yet the Problem Remains”: Why Genetic Determinism Still Haunts Biomedical Research
ABSTRACT After the horrors of the Holocaust and its connections to eugenics were revealed to the world, many post‐war population geneticists sought to establish rhetorical distance from the Nazi's state‐led campaigns, without abandoning their belief that actively shaping the population's genetics would produce a prosperous society.
Christopher R. Donohue, Ian A. Myles
wiley +1 more source
Systolic overload increases the synthesis of cardiac proteins, both misfolded and native, leading to cardiac hypertrophy and elevated proteostasis burden. Meanwhile, systolic overload also increases Ser14‐RPN6 phosphorylation (pS14‐RPN6), thereby increasing proteasome (Psm) proteolytic capacity and meeting the increased demand for protein degradation ...
Md. Salim Ahammed +7 more
wiley +1 more source
Análise de QTL com estudo de genes candidatos para comportamentos relacionados à emocionalidade e ao consumo de etanol usando um modelo genético composto pelas linhagens de ratos Lewis e SHR [PDF]
Tese(doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-graduação em FarmacologiaOs ratos das linhagens isogênicas Lewis (LEW) e spontaneously hipertensive rats (SHR) diferem em uma série de aspectos ...
Izídio, Geison de Souza
core
Estudo da associação entre duas regiões do genoma do rato, localizadas nos cromossomos 4 e 7, e a emocionalidade em duas linhagens de ratos selecionadas no teste do campo aberto [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-graduação em NeurociênciasAs linhagens de ratos Floripa H e Floripa L, selecionadas bidirecionalmente para extremos de locomoção no centro do ...
Hameister, Thaís Muller
core
Objective:: Being visually impaired increases the likelihood of sleep disorders and altered behavior. This study investigated physiological and behavioral differences in two similar mice substrains when exposed to constant light (LL) - CBA/J with retinal
Hannah V Deane +4 more
doaj +1 more source
Acoustic startle and prepulse inhibition in 40 inbred strains of mice.
A high-throughput phenotype screening protocol was used to measure the acoustic startle response (ASR) and prepulse inhibition (PPI) in mice. ASRs were evoked by noise bursts; prepulses for PPI were 70 dB sound pressure level tones of 4, 12, and 20 ...
O\u27Steen, J +5 more
core +1 more source
Sexual Abnormalities in an Inbred Strain of Mice
An interesting sexual abnormality was observed in the Little-Murray dilute brown strain of mice. To date this abnormality has been observed in 10 animals, and is evidently hereditary. All the abnormal individuals were descendants of the same pair of mice, the ancestors of which were inbred by brother to sister matings for many generations.
openaire +1 more source
Decrease of vanillin sucrose intake by victorious and defeated mice: development of anhedonia? [PDF]
Hedonic reactions to various rewards play a key role in various forms of motivated behavior. The influence of repeated experience of social victories or defeats in daily agonistic interactions between male mice on voluntary consumption of vanillin ...
Damira F. Avgustinovich +3 more
core
A quantitative study of cerebrovascular variation in inbred mice.
The arteries of the base of the mouse brain were examined after perfusion with India ink. A qualitative difference exists between inbred mice of three strains (C57BL/6J, 129/J and BALB/cCF) on the one hand, and genetically defined heterogeneous mice ...
Miceli, D +3 more
core +1 more source

