Results 131 to 140 of about 106,084 (256)
Acoustic startle and prepulse inhibition in 40 inbred strains of mice.
A high-throughput phenotype screening protocol was used to measure the acoustic startle response (ASR) and prepulse inhibition (PPI) in mice. ASRs were evoked by noise bursts; prepulses for PPI were 70 dB sound pressure level tones of 4, 12, and 20 ...
O\u27Steen, J +5 more
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Análise de QTL com estudo de genes candidatos para comportamentos relacionados à emocionalidade e ao consumo de etanol usando um modelo genético composto pelas linhagens de ratos Lewis e SHR [PDF]
Tese(doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-graduação em FarmacologiaOs ratos das linhagens isogênicas Lewis (LEW) e spontaneously hipertensive rats (SHR) diferem em uma série de aspectos ...
Izídio, Geison de Souza
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Intra- and inter-individual genetic differences in gene expression
Genetic variation is known to influence the amount of mRNA produced by a gene. Given that the molecular machines control mRNA levels of multiple genes, we expect genetic variation in the components of these machines would influence multiple genes in a ...
Cotsapas, Chris J. +26 more
core +1 more source
Sexual Abnormalities in an Inbred Strain of Mice
An interesting sexual abnormality was observed in the Little-Murray dilute brown strain of mice. To date this abnormality has been observed in 10 animals, and is evidently hereditary. All the abnormal individuals were descendants of the same pair of mice, the ancestors of which were inbred by brother to sister matings for many generations.
openaire +1 more source
Immune endotypes in tuberculosis: Keys to decoding disease complexity
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor +4 more
wiley +1 more source
Abstract The cross‐sectional Master Athletic Laboratory Study of Intramuscular Connective Tissue (MALICoT, DRKS00015764) examined effects of athletic exercise and age on endomysium content in human soleus muscle. Forty‐three clinically healthy male participants were grouped into young (20–35 years) nonphysically active controls (n = 12), young power ...
Christoph S. Clemen +6 more
wiley +1 more source
The evidence for old age motor neuron death: A scoping review
We systematically evaluated the extant literature on age‐related motor neuron (MN) death in aging, focusing on studies directly assessing MNs. We show that in the spinal cord and brainstem, there is robust evidence for MN loss, particularly in the human spinal cord. In rats, MN loss was readily observed across a variety of labelling methods and regions,
Sang Won Cheung, Matthew J. Fogarty
wiley +1 more source
All mice were >8 weeks old at time of phenotyping. (A) Testis weight standardized by body weight for inbred Nachman strains and three derivative F1 hybrids.
Hilda Opoku Frempong (18340502) +14 more
core +1 more source
Statement on the findings presented in the Toxicological Profile for Mercury issued by the US ATSDR
Abstract The European Food Safety Authority (EFSA) was requested by the European Commission to deliver a statement on the findings presented in the Toxicological Profile for Mercury issued by the US Agency for Toxic Substances and Disease Registry (ATSDR) in 2024. The statement was endorsed by the CONTAM Panel before approval by EFSA. Although some key
European Food Safety Authority (EFSA) +7 more
wiley +1 more source
A quantitative study of cerebrovascular variation in inbred mice.
The arteries of the base of the mouse brain were examined after perfusion with India ink. A qualitative difference exists between inbred mice of three strains (C57BL/6J, 129/J and BALB/cCF) on the one hand, and genetically defined heterogeneous mice ...
Miceli, D +3 more
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