Results 101 to 110 of about 1,877,211 (239)

Intra- and inter-individual genetic differences in gene expression [PDF]

, 2008
Genetic variation is known to influence the amount of mRNA produced by a gene. Given that the molecular machines control mRNA levels of multiple genes, we expect genetic variation in the components of these machines would influence multiple genes in a ...
Cotsapas, Chris J., Liu, M.Y., Cowley, Mark J., Nott, David J., Little, Peter F., Peter F. R. Little, Chan, E.K.F., Cotsapas, C.J., Chan, Eva K., Luo, Oscar J., Cowley, M.J., Williams, Rohan B., Eva K. F. Chan, Pulvers, Jeremy N., Michael Y. Liu, Rohan B. H. Williams, Pulvers, J.N., David J. Nott, Williams, R.B.H., Little, P.F.R., Jeremy N. Pulvers, Oscar J. Luo, Mark J. Cowley, Luo, O.J., Chris J. Cotsapas, Nott, D.J., Liu, Michael Y.   +26 more
core   +1 more source

Ordered Chaos: Photoreceptor Mosaics in the Larval and Adult Turquoise Killifish (Nothobranchius furzeri)

Journal of Comparative Neurology, Volume 534, Issue 9, September 2026.
The annual turquoise killifish (Nothobranchius furzeri) cone photoreceptor mosaic is an ordered lattice but lacks regularity of cone subtypes in adulthood. The cone mosaic differs between life stages and has characteristics observed in other fishes adapted for life in turbid water.
Nicole C. L. Noel
wiley   +1 more source

Neurodevelopmental Alterations in Inhibitory Interneurons of Cortex, Hippocampus, and Striatum of Genetic Absence Epilepsy Rats

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Schematic conceptual model illustrating the proposed temporally distinct contributions of cortical interneuron populations to absence seizure maturation in GAERS shown within thalamocortical loop (VPM–TRN–cortex). Early PV+ interneuron upregulation primes cortical networks for SWD initiation, while later SST+ interneuron increases in M1 cortex ...
Nihan Çarçak, Elif Tuğçe Erdeve, Courtney J. Wright, Elif Keskinöz, My Andersson, Filiz Onat, Deniz Kırık   +6 more
wiley   +1 more source

Identifying reliable traits across laboratory mouse exploration arenas: A meta-analysis [PDF]

, 2012
This study is a meta-analysis of 367 mice from a collection of behaviour neuroscience and behaviour genetic studies run in the same lab in Zurich, Switzerland.
Rime Madani, Michael J. Galsworthy, Hans-Peter Lipp   +2 more
core   +1 more source

Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models.

PLoS Genetics
The laboratory mouse has served as the premier animal model system for both basic and preclinical investigations for over a century. However, laboratory mice capture only a subset of the genetic variation found in wild mouse populations, ultimately ...
Beth L Dumont, Daniel M Gatti, Mallory A Ballinger, Dana Lin, Megan Phifer-Rixey, Michael J Sheehan, Taichi A Suzuki, Lydia K Wooldridge, Hilda Opoku Frempong, Raman Akinyanju Lawal, Gary A Churchill, Cathleen Lutz, Nadia Rosenthal, Jacqueline K White, Michael W Nachman   +14 more
doaj   +1 more source

The genetic architecture of NAFLD among inbred strains of mice

eLife, 2015
To identify genetic and environmental factors contributing to the pathogenesis of non-alcoholic fatty liver disease, we examined liver steatosis and related clinical and molecular traits in more than 100 unique inbred mouse strains, which were fed a diet
Simon T Hui, Brian W Parks, Elin Org, Frode Norheim, Nam Che, Calvin Pan, Lawrence W Castellani, Sarada Charugundla, Darwin L Dirks, Nikolaos Psychogios, Isaac Neuhaus, Robert E Gerszten, Todd Kirchgessner, Peter S Gargalovic, Aldons J Lusis   +14 more
doaj   +1 more source

High‐Density SNP Genotyping Reveals High Population Connectivity and Limited Spatial Genetic Structure in Apodemus flavicollis and Apodemus sylvaticus

Ecology and Evolution, Volume 16, Issue 9, September 2026.
We evaluated the performance of a high‐density cross‐species SNP array to discriminate and genetically characterise Apodemus flavicollis and Apodemus sylvaticus in a fragmented agriforest landscape. The SNP data clearly separated the two species and revealed high genetic diversity, weak spatial genetic structure and no isolation‐by‐distance within each
Maria Chiara Fabbri, Matilde Martini, Giovanna Donati, Giuseppe Coiro, Giuseppe Luzzi, Luciano Ferraro, Donata Coppola, Riccardo Bozzi   +7 more
wiley   +1 more source

Digit ratio (2Dratio4D) differences between 20 strains of inbred mice.

PLoS ONE, 2009
The second to fourth digit ratio (2Dratio4D) is sexually differentiated in a variety of species, including humans, rats, birds, and lizards. In humans, this ratio tends to be lower in males than in females.
Reginia H Y Yan, Mark Bunning, Douglas Wahlsten, Peter L Hurd   +3 more
doaj   +1 more source

Baat‐Deficient Mice Recapitulate Elevated 7α‐Hydroxy‐3‐Oxo‐4‐Cholestenoic Acid Observed in a Japanese Patient With BAAT Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACTBile acid Coenzyme A: amino acid N‐acyltransferase (BAAT) catalyzes the conjugation of bile acids with taurine or glycine, a process essential for bile acid solubility and intestinal lipid absorption. Mutations in BAAT cause an inborn error of bile acid metabolism, typically characterized by reduced conjugated bile acids and fat‐soluble vitamin
Soma Koga, Hajime Takei, Ryutaro Tamura, Yugo Takaki, Hiroyuki Kusuhara, Hiroshi Nittono, Hisamitsu Hayashi   +6 more
wiley   +1 more source

Standardized Nomenclature for Inbred Strains of Mice: eighth listing.

, 1985
This paper presents a list of inbred strains of mice with their origins and characteristics, and a list of standard subline ...
Staats, J
core   +1 more source