Results 151 to 160 of about 128,575 (177)

Cd‐metallothionein nephrotoxicity in inbred strains of mice

Journal of Toxicology and Environmental Health, 1992
Genetic differences in the acute hepatic and testicular toxicity of Cd occur among different strains of mice. However, it is not known whether genetic variation to the renal damage caused by Cd-metallothionein (CdMT) exists. Therefore, male mice of the C3H/HeJ, C57/Bl10, CBA/CA, and DBA/2J strains, previously shown to differ in hepatic and testicular ...
Curtis D. Klaassen, W.C. Kershaw, L.E. Sendelbach, F. Cuppage   +3 more
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Gene Trees and the Origins of Inbred Strains of Mice

Science, 1991
Extensive data on genetic divergence among 24 inbred strains of mice provide an opportunity to examine the concordance of gene trees and species trees, especially whether structured subsamples of loci give congruent estimates of phylogenetic relationships.
William R. Atchley, Walter M. Fitch
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Development of a highly fecund inbred strain of mice

Mammalian Genome, 2004
A highly fecund inbred mouse line has been established from the Quackenbush Swiss (QS) outbred strain by full-sib inbreeding combined with selection for high number of pups born alive (NBA) and low interlitter interval (ILI). After more than 50 generations of inbreeding and selection, this line, named QSi5, has an NBA of 13.4 and an ILI of 29 days ...
Chris Moran, I. C. A. Martin, John W. James, Marte Holt, Frank W. Nicholas   +4 more
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How pure are inbred strains of mice?

Immunology Today, 1982
As useful as immunologists find the inbred mouse, they cannot help but become disenchanted when they encounter genetically disparate mice in a purportedly inbred strain. Genetic impurity (allogenicity) can arise from a number of sources: incomplete inbreeding, mutation, inadvertent outcrossing, mislabeling, and epislatic and heterozygote selection.
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Evolution in Inbred Strains of Mice Appears Rapid

Science, 1985
Genetic variation at 97 loci in ten commonly used inbred strains of mice is greatly in excess of that expected under current assumptions. Evidence against all of the readily apparent explanations is presented and the possibility of early selection for heterozygosity or of conversion is suggested.
William R. Atchley, Walter M. Fitch
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Inbred Strains of Mice

1979
Inbred mice have been used more extensively than those of any other species of laboratory mammal. A total of about 230 strains are listed here, but some of the more widely used strains have become divided into sublines among which there are detectable genetic differences. Some strains are recorded in the literature but are now extinct.
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Corticosterone Response to Ethanol in Inbred Strains of Mice

Nature, 1968
ETHANOL acts as a stressor in activating the pituitary adrenal axis1–3 and also induces narcosis in mammals. In mice there are strain differences in ethanol-induced narcosis, measured by sleeping time4,5. We have studied the relationship between genotype in inbred mouse strains and the action of ethanol as a stressor.
Kakihana, R, Noble, E P, Butte, J C
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Toxicokinetics of trimethyltin in four inbred strains of mice

Toxicology Letters, 1998
Sixteen week old male AKR/J, Balb/cByJ, C57B1/6J and DBA/2J mice received single i.p. injections of trimethyltin (TMT). The toxic effects were weight loss, hyperexcitability, tremor, clonic-tonic convulsion, posterior paresis and death. The minimum toxic dose was 1.8 mg/kg, for the AKR strain and 2.3 mg/kg for the other strains.
Ahmed H. Hikal, John C. Matthews, Jethro E. Ekuta   +2 more
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Mating behaviour of two inbred strains of mice

Animal Behaviour, 1966
Summary Observations were made of the mating patterns of males from two inbred strains, ST/J and CBA/J, with females from both of these strains. Experiment I involved single males that were housed separately, while experiment II involved inter-strain pairs of males that were housed together. In three out of the four possible situations, the ST males
Levine, L, Barsel, G E, Diakow, C A
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TRANSPLANTATION OF THYMIC TISSUE IN INBRED STRAINS OF MICE

Journal of Endocrinology, 1961
SUMMARY Thymic tissue has been transplanted between donor and host mice of different ages. It has been found that thymic tissue more than a few days old loses weight rapidly when transplanted to a host, and that beyond this age loss of weight is independent of the age of either donor or host.
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