Results 201 to 210 of about 1,780,625 (304)

Broussoflavonol F Alleviates Obesity-Associated Metabolic Syndrome in Obese Mice by Modulating Gut Microbiota. [PDF]

Mol Nutr Food Res
Zhao C, Huang Q, Zhang S, Han Y, Tu Y, Zhu Z.   +5 more
europepmc   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Obesity Increases Atherosclerosis Susceptibility via an Intertissue miR-30e-SLC7A11 Axis. [PDF]

Circ Res
Wang C, She J, Qian X, Wu H, Hao W, Liang X, Guo N, Dai X, He F, He S, Zhang J, Lei Y, Zhuo X, Li H, Luo Y, Deng K, Liu Y, Gao S, Yuan X, Liu H, Bai T, Xiong Y, Shyy JY, Yuan ZY.   +23 more
europepmc   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

Maternal metformin treatment in obese pregnant dams normalizes neonatal sensory-motor reflexes. [PDF]

Mol Cell Pediatr
Müller-Limberger E, Frederick B, Hansen S, Wohlfarth M, Janoschek R, Mahabir E, Fischer P, Gründemann D, Kalis S, Alejandre Alcázar MA, Dötsch J, Hucklenbruch-Rother E, Appel S.   +12 more
europepmc   +1 more source

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

BMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv, Xinyi Chao, Jiamin Zhang, Jianfeng Liu   +3 more
wiley   +1 more source

Targeting circulating fatty acid-binding protein 4 ameliorates obesity-associated hepatic steatosis. [PDF]

JHEP Rep
Jiang X, Avellino A, Yu J, Liu S, Zhao L, Wang Z, Han X, Thakkar H, Shilyansky J, Xu Z, Schnicker N, Chaurasia B, Bosch DE, Hao J, Zhang X, Sugg SL, Li B.   +16 more
europepmc   +1 more source

Baseline Body Mass Index Category and Incident Treated Hypertension in Australian Men: A Linked Prospective Cohort Study Using PBS/MBS Data

Chronic Diseases and Translational Medicine, EarlyView.
Kaplan–Meier hypertension‐free survival by baseline body mass index category, primary adult cohort (men aged ≥ 18 years, n = 12,742). Time since baseline in years is plotted on the horizontal axis and the probability of remaining free of treated hypertension is plotted on the vertical axis. Numbers at risk are shown beneath the plot.
Ebenezer Afrifa‐Yamoah
wiley   +1 more source

Adipocyte-Derived KIF13B Aggravates Obesity-Associated Metabolic Dysfunction via LRP1/PPARγ Signaling. [PDF]

MedComm (2020)
Miao G, Li Z, Zhang L, Xu Y, Wang Z, Wang Z, Xian A, Zheng L, Chen J, Han Y, Shan C, Lu K, Tao M, Zhang L, Zhang W, Huang W, Wang Y, Wei R, Dong E, Xian X.   +19 more
europepmc   +1 more source

Dietary Artificial Sweeteners: From Chemical Transformation in Food to Gut Microbial Processing

ChemFoodChem, EarlyView.
This review article unites classical and recent findings on the stability of artificial sweeteners in food. The focus is on ten sweeteners approved in the European Union: their chemical stability during processing and storage, individual degradation products, and their interactions with the intestinal microbiota.
Jürgen Lassak, Michael Hellwig
wiley   +1 more source