Results 111 to 120 of about 6,887,725 (399)

The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage. [PDF]

open access: yes, 2019
The type I TGFβ receptor TGFβRI (encoded by Tgfbr1) was ablated in cartilage. The resulting Tgfbr1 Col2 mice exhibited lethal chondrodysplasia. Similar defects were not seen in mice lacking the type II TGFβ receptor or SMADs 2 and 3, the intracellular ...
Baek, Jongseung   +7 more
core  

Of Mice and Renin [PDF]

open access: yesHypertension, 2017
See related article, pp 119–128 Organisms tend to compensate for the need of a cellular function by increasing the amount or the size of the responsible cell type. Hypertrophy of all muscle types under increased workload is a prominent example. Also several hormone systems react by increasing the amount of hormone-producing cells, when the main ...
openaire   +2 more sources

Evaluation of anti-inflammatory, anti-nociceptive, and anti-pyretic potential of hydroalcoholic extract of Trifolium pratense in mice

open access: yesComplementary Medicine Journal of Faculty of Nursing and Midwifery, 2019
Introduction: There are some reports in traditional medicine concerning the anti-inflammatory, anti-nociceptive and anti-pyretic effects of Trifolium pretense (red clover).
Parandin R
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

ACATALASEMIC MICE [PDF]

open access: yesProceedings of the National Academy of Sciences, 1964
Feinstein, R N   +3 more
openaire   +2 more sources

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans Published, JLR Papers in Press, September 8, 2005. DOI 10.1194/jlr.M500294-JLR200

open access: yesJournal of Lipid Research, 2005
Macrophage infiltration of white adipose tissue (WAT) is implicated in the metabolic complications of obesity. The precipitating event(s) and function(s) of macrophage infiltration into WAT are unknown.
S. Cinti   +9 more
semanticscholar   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice [PDF]

open access: gold, 2020
Zhi Ruan   +6 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Salt marsh harvest mouse abundance and site use in a managed marsh [PDF]

open access: yes, 2009
The salt marsh harvest mouse (Reithrodontomys raviventris) is a federal and California listed endangered mammal endemic to the San Francisco Bay. The objectives of this research were to determine habitat use of endangered salt marsh harvest mice in a ...
Basson, Galli
core   +1 more source

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