Results 121 to 130 of about 4,772,082 (338)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Three‐level secondary negawatt trading market mechanism with capability of congestion management

open access: yesIET Smart Grid
Modern power markets are witnessing various energy transactions, and the participants are focusing on different objectives like energy cost, profit, and environmental concerns as key parts of their strategy.
Amirhossein Amirmahani   +2 more
doaj   +1 more source

The increasing of potential in tourism logistics supply chain to Khon Kaen ME city, Thailand. [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2019
This research aims to study the situation of tourism logistics supply chain in Khon Kaen ME city and to conduct and study the SWOT analysis of tourism logistics supply chain in Khon Kaen ME city. Recommendations are also made for increasing the potential
Patipat Tunming   +2 more
doaj  

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

A local cuisine tourism approach to authenticity and a sense of place for Postmodern gastronomy in I-SAN Thailand. [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2019
This study aims to study local cuisine culture in the Chiang Khan District of Loei Province in Northeastern Thailand by performing an examination and analysis through the use of external and internal environment analysis (SWOT Analysis) and by creating ...
Asst. Prof. Dr. Thirachaya Chaigasem   +1 more
doaj  

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Mice and Beetles [PDF]

open access: yesNature, 1879
PERMIT me to ask, through the medium of your columns, if it is known whether mice kill the common kitchen black-beetle. I have been unable to find anything bearing upon this subject, but having observed that there is an apparent reduction in the number of beetles, or at least no increase in number while the mice are permitted to live, and also that the
openaire   +2 more sources

Home - About - Disclaimer - Privacy