Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries [PDF]
Transient receptor potential canonical type 3 (TRPC3) channels are non-selective cation channels and regulate intracellular Ca2+ concentration. We examined the role of TRPC3 channels in agonist-, membrane depolarization (high K+)-, and mechanical ...
Abramowitz, Joel +6 more
core +11 more sources
Towards a sustainable city through system innovation implementation: Case study of reinventing Kebon Sirih Jakarta as an inclusive tourism spot [PDF]
A tourism spot at the heart of the Jakarta-capital city of Indonesia is facing a crisis due to the fast-growing city development. Action research to revitalize Kebon Sirih tourism is implemented.
Augustine Adibroto Tusy +3 more
doaj +1 more source
Background The serotonin (5-HT) system has long been implicated in autism spectrum disorder (ASD) as indicated by elevated whole blood and platelet 5-HT, altered platelet and brain receptor and transporter binding, and genetic linkage and association ...
Jacob Ellegood +7 more
doaj +1 more source
Bi-objective modeling approach for repairing multiple feature infrastructure systems [PDF]
A bi-objective decision aid model for planning long-term maintenance of infrastructure systems is presented, oriented to interventions on their constituent elements, with two upgrade levels possible for each element (partial/full repairs). The model aims
Almeida, Luís Alçada +2 more
core +1 more source
Restless legs syndrome (RLS) is a neurological disorder that entails an urge to move with a circadian pattern during the evening/night. RLS may be accompanied by decreased sleep time and increased occurrence of periodic leg movements during sleep (PLMS),
Viviana Lo Martire +8 more
doaj +1 more source
Particle swarm optimization with sequential niche technique for dynamic finite element model updating [PDF]
Peer ...
Abdel-Ghaffar +74 more
core +1 more source
Length Influences on Lateral Performance of Barrette from Three-Dimensional Finite Element Analysis
The performance of a single barrette subjected to the lateral load applied at its top is presented in this paper using three-dimensional finite element analyses based on the Midas GTS program.
Der-Wen Chang +5 more
doaj +1 more source
Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. [PDF]
Cytochrome P450 (CYP) monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs) that have multiple biological actions.
Hammock, Bruce D +5 more
core +3 more sources
Background Recent findings from studies of mouse models of Mendelian disorders of epigenetic machinery strongly support the potential for postnatal therapies to improve neurobehavioral and cognitive deficits. As several of these therapies move into human
Sarah Jessica Goodman +6 more
doaj +1 more source
Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]
Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H. +4 more
core +2 more sources

