Results 211 to 220 of about 2,593,743 (268)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Lost in Sleep Transition: Tangled Sleep and Thermoregulation in Dravet Syndrome. [PDF]

Epilepsy Curr
Wong JC.
europepmc   +1 more source

Of mice and men.

EMBO reports, 2004
Ben‐Neriah, Yinon, Schmitz, M Lienhard
openaire   +2 more sources

β-Hydroxybutyrate Improves Glucose Metabolism in Streptozotocin-Induced Type 1 Diabetes by Inhibiting Gut and Liver Glucose Transporters via GPR109A. [PDF]

Diabetes
Li S, Wang J, Xin C, Dong Y, Xie A, Song J, Wan J, Yin J.   +7 more
europepmc   +1 more source

TL1A/DR3 signaling deletion attenuates mucosal inflammation and alveolar bone loss in a murine model of spontaneous periodontitis. [PDF]

Proc Natl Acad Sci U S A
Di Nicolantonio S, Miranda MR, Gomez-Nguyen A, Pietropaoli D, Monaco A, Menghini P, Cominelli F.   +6 more
europepmc   +1 more source

Aging and Western Diet Synergistically Impair Hepatic Thyroid Hormone Signaling to Promote Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Mice. [PDF]

Aging Cell
Zhang X, Tripathi M, Goh CT, Chan CS, Boelen A, Yen PM, Singh BK, Bruinstroop E.   +7 more
europepmc   +1 more source

Oxidized PDI promotes thrombus formation in oxidative stress. [PDF]

Blood
Yang M, Owegie OC, Patel A, Kennedy QP, Flaumenhaft JT, Chinnaraj M, Ponzar N, Fulcidor EM, Rico MC, Bhowmik A, Carroll KS, Handy DE, Loscalzo J, Essex DW, Pozzi N, Flaumenhaft R.   +15 more
europepmc   +1 more source

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Biozzi mice: Of mice and human neurological diseases

Journal of Neuroimmunology, 2005
In 1972 Guido Biozzi selectively bred mice to study the immunopathological mechanisms underlying polygenic diseases. One line, the Biozzi antibody high (AB/H) mouse (now designated the ABH strain) was later found to be highly susceptible to many experimentally induced diseases such as autoimmune encephalomyelitis, autoimmune neuritis, autoimmune ...
Amor, S, Smith, PA, Hart, Boris, Baker, D   +3 more
openaire   +3 more sources