Results 241 to 250 of about 6,887,725 (399)

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Cell-Specific Inducible Human <i>APOL1</i> Risk Variant Expression in Mice Causes Hypertension and Renal Damage. [PDF]

Circulation
Li F, Poudel B, Andrade-Silva M, Wu J, Raman A, Cruz-Morales E, Wahba J, Vassalotti A, Li C, Abedini A, Klötzer KA, Ding X, Hunter CA, Miner JJ, Susztak K.   +14 more
europepmc   +1 more source

Intracellular Regeneration of Glucocorticoids by11β-Hydroxysteroid Dehydrogenase (11β-HSD)-1 Plays a KeyRole in Regulation of the Hypothalamic-Pituitary-Adrenal Axis: Analysisof 11β-HSD-1-Deficient Mice**The Wellcome Trust supported this work through a program grant (to J.J.M. and J.R.S.) and a Career Development Fellowship (to M.C.H.). [PDF]

, 2001
Hayley J. Harris, Yuri Kotelevtsev, John J. Mullins, Jonathan R. Seckl, Megan C. Holmes   +4 more
openalex   +1 more source

Use of the Open Field Maze to measure locomotor and anxiety-like behavior in mice.

Journal of Visualized Experiments, 2015
M. Seibenhener, M. Wooten
semanticscholar   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Sex-related upregulation of bone morphogenetic protein signaling inhibits adult neurogenesis in APP^NL-G-F alzheimer's disease model mice. [PDF]

Biol Sex Differ
Su X, Takayanagi R, Maeda H, Saido TC, Ohshima T.   +4 more
europepmc   +1 more source

Pasteurized Akkermansia muciniphila improves irritable bowel syndrome-like symptoms and related behavioral disorders in mice [PDF]

Maëva Meynier, Valentine Daugey, Geoffroy Mallaret, Sandie Gervason, Mathieu Méleine, Julie Barbier, Youssef Aissouni, Stéphane Lolignier, Mathilde Bonnet, Denis Ardid, Willem M. de Vos, Matthias Van Hul, Peter Suenaert, Amandine Brochot, Patrice D. Cani, Frédéric A. Carvalho   +15 more
openalex   +1 more source

Bacillus anthracis Edema Toxin Causes Extensive Tissue Lesions and Rapid Lethality in Mice [PDF]

, 2005
Aaron M. Firoved, Georgina Miller, Mahtab Moayeri, Rahul Kakkar, Yuequan Shen, Jason F. Wiggins, Elizabeth M. McNally, Wei‐Jen Tang, Stephen H. Leppla   +8 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Connexin 36-mediated gap junctions contribute to fine odour discrimination and late-phase excitation of mitral cells in the mouse olfactory bulb. [PDF]

J Physiol
Kuruppath P, Jones ST, Pouille F, Ramirez-Gordillo D, Restrepo D, Schoppa NE.   +5 more
europepmc   +1 more source