Results 251 to 260 of about 6,887,725 (399)

The gut microbiota influences blood-brain barrier permeability in mice

open access: yesScience Translational Medicine, 2014
V. Braniste   +17 more
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

open access: yesFEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama   +7 more
wiley   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

Syngap1 and the development of murine neocortical progenitor cells. [PDF]

open access: yesNat Commun
Barão S   +4 more
europepmc   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

High-Protein Diet Exacerbates Insulin Resistance via the JNK/IKKβ-IRS-1 Pathway. [PDF]

open access: yesEndocrinol Diabetes Metab
Li J   +13 more
europepmc   +1 more source

Failure of Epithelial Tube Maintenance Causes Hydrocephalus and Renal Cysts in Dlg5 Mice [PDF]

open access: bronze, 2007
Tamilla Nechiporuk   +2 more
openalex   +1 more source

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