Results 21 to 30 of about 4,772,082 (338)

Migraines in Mice? [PDF]

open access: yesCell, 1996
Altered ion permeability would clearly affect intercellular signaling and may precipitate the paroxysmal episodes. But how can a channelopathy generate a prolonged paroxysmal event? The episodic events observed in FHM/EA-2 and tottering/leaner generally last for tens of minutes to tens of hours; the shortest events, the spike and wave discharges ...
openaire   +3 more sources

Echocardiography in Mice [PDF]

open access: yesCurrent Protocols in Mouse Biology, 2011
AbstractMurine models have been utilized with increasing frequency mainly due to availability of genetically engineered models. With advancement in high spatial and temporal resolution, echocardiography is used extensively for the evaluation of cardiovascular function in murine models of cardiovascular disease.
Dorothy E. Vatner   +3 more
openaire   +3 more sources

Effects of Raw Ethanolic Seed Extract of Tetracarpidium conophorum on Heamatological and Histopathological Parameters in Swiss Albino Mice Infected with Plasmodium berghei [PDF]

open access: yes, 2017
Study was carried out to determine the heamatological and histopathological effects of raw ethanolic seed extract of Tetracarpidium conophorum in swiss albino mice infected with Plasmodium berghei (NK65).
D. A. Oloruntola   +3 more
core   +1 more source

Delayed Tibial-platform Periprosthetic Stress Fracture after Unicompartmental Knee Arthroplasty: Uncommon and Devastating Complication

open access: yesJournal of Orthopaedics, Trauma and Rehabilitation, 2018
Periprosthetic fracture around total knee arthroplasty (TKA) is a well-described complication. Yet, report of medial tibial plateau stress fracture after unicompartmental knee arthroplasty (UKA) is limited.
Hung Yuk-Wah   +4 more
doaj   +1 more source

Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. [PDF]

open access: yes, 2016
Cytochrome P450 (CYP) monooxygenases epoxidize the omega-3 polyunsaturated fatty acid (PUFA) docosahexaenoic acid into novel epoxydocosapentaenoic acids (EDPs) that have multiple biological actions.
Hammock, Bruce D   +5 more
core   +3 more sources

Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]

open access: yes, 2010
Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H.   +4 more
core   +2 more sources

PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity. [PDF]

open access: yes, 2019
(1) Background: Paraoxonase 2 (PON2) is a ubiquitously expressed protein localized to endoplasmic reticulum and mitochondria. Previous studies have shown that PON2 exhibits anti-oxidant and anti-inflammatory functions, and PON2-deficient (PON2-def) mice ...
Fogelman, Alan M   +9 more
core   +1 more source

Identification of a Chromosome 1 Substitution Line B6-Chr1BLD as a Novel Hyperlipidemia Model via Phenotyping Screening

open access: yesMetabolites, 2022
Hyperlipidemia is a chronic disease that seriously affects human health. Due to the fact that traditional animal models cannot fully mimic hyperlipidemia in humans, new animal models are urgently needed for basic drug research on hyperlipidemia. Previous
Xu Li   +6 more
doaj   +1 more source

An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice [PDF]

open access: yes, 2013
Interleukin (IL)-33, the most recent member of the IL family of cytokines, signals through the ST2 receptor. IL-33/ST2 signaling mediates antigen challenge-induced mechanical hyperalgesia in the joints and cutaneous tissues of immunized mice. The present
Alves-Filho, J.C.   +9 more
core   +3 more sources

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