Results 51 to 60 of about 4,772,082 (338)

The use of tourism consumption estimations to assess the economic effects of tourism in metropolitan cities as exemplified by Warsaw

Ekonomiczne Problemy Turystyki, 2018
The article aims to present possible use of tourism consumption estimations for the assessment of the economic effects of tourism in metropolitan cities as exemplified by Warsaw, followed by their application as a support tool for urban development ...
EWA DZIEDZIC, TERESA SKALSKA, ROBERT VINCZE   +2 more
doaj   +1 more source

Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179 [PDF]

, 2015
The rd1 mouse with a mutation in the Pde6b gene was the first strain of mice identified with a retinal degeneration. However, AAV-mediated gene supplementation of rd1 mice only results in structural preservation of photoreceptors, and restoration of the ...
Ali, RR, Azam, SA, Bainbridge, JW, Carvalho, LS, Duran, Y, Holthaus, SM, Luhmann, UF, Nishiguchi, KM, Powell, K, Ribeiro, J, Rizzi, M, Smith, AJ   +11 more
core   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Salt marsh harvest mouse abundance and site use in a managed marsh [PDF]

, 2009
The salt marsh harvest mouse (Reithrodontomys raviventris) is a federal and California listed endangered mammal endemic to the San Francisco Bay. The objectives of this research were to determine habitat use of endangered salt marsh harvest mice in a ...
Basson, Galli
core   +1 more source

Beach Mice

EDIS, 1969
This document is WEC 165, one of a series of the Wildlife Ecology and Conservation Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida.
Brittany L. Bird, Lyn C. Branch, Mark E. Hostetler   +2 more
openaire   +5 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

TSG101 depletion dysregulates mitochondria and PML NBs, triggering MAD2-overexpressing interphase cell death (MOID) through AIFM1-PML-DAXX pathway

Cell Death and Disease
Overexpression of mitotic arrest deficiency 2 (MAD2/MAD2L1), a pivotal component of the spindle assembly checkpoint (SAC), resulted in many types of cancer.
Yao Xi, Rui Xu, Shengnan Chen, Jiezhu Fang, Xiang Duan, Yidan Zhang, Guoli Zhong, Zhifei He, Yan Guo, Xinyu Li, Wenzhi Tao, Yang Li, Yan Li, Lei Fang, Yohei Niikura   +14 more
doaj   +1 more source

Studying the principles of sustainable tourism development in Karabakh [PDF]

BIO Web of Conferences
This article explores the fundamentals of the sustainable development concept, where the dominant factor is the creation of harmony in the functioning of the nature-society system.
Khusainova Irada, Gasimova Afet Ayat, Mammadova Ilaha Isa, Yekimov Sergey, Tahirzade Jamala Fizuli, Khalilova Ramida Farrukh, Sobirov Bobur   +6 more
doaj   +1 more source

Innate immune basis for rift valley fever susceptibility in mouse models [PDF]

, 2017
Rift Valley fever virus (RVFV) leads to varied clinical manifestations in animals and in humans that range from moderate fever to fatal illness, suggesting that host immune responses are important determinants of the disease severity. We investigated the
Bruhns, Pierre, Flamand, Marie, Godon, Ophélie, Jouvion, Grégory, Lathan, Rashida, Malissen, Marie, Panthier, Jean-Jacques, Simon-Chazottes, Dominique   +7 more
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source