Results 61 to 70 of about 4,772,082 (338)

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Brief Maternal Separation Inoculates Against the Effects of Social Stress on Depression-Like Behavior and Cocaine Reward in Mice

Frontiers in Pharmacology, 2022
Exposure to intermittent repeated social defeat (IRSD) increases the vulnerability of mice to the rewarding effects of cocaine in the conditioned place preference (CPP) paradigm.
C. Calpe-López, M. A. Martínez-Caballero, M. P. García-Pardo, M. A. Aguilar   +3 more
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Scorias spongiosa Polysaccharides Promote the Antioxidant and Anti-Inflammatory Capacity and Its Effect on Intestinal Microbiota in Mice

Frontiers in Microbiology, 2022
Scorias spongiosa, as an edible fungus, has multiple health benefits. However, the effects of S. spongiosa on intestinal health are rarely explored. Hence, our study aims to elaborate on the influences of S.
Yingyin Xu, Yingyin Xu, Yingyin Xu, Zhiyuan Zhang, Zhiyuan Zhang, Zhiyuan Zhang, Huiyu Feng, Jie Tang, Jie Tang, Jie Tang, Weihong Peng, Weihong Peng, Weihong Peng, Ying Chen, Ying Chen, Ying Chen, Jie Zhou, Jie Zhou, Jie Zhou, Yong Wang, Yong Wang, Yong Wang   +21 more
doaj   +1 more source

The role of glacier mice in the invertebrate colonisation of glacial surfaces: the moss balls of the Falljökull, Iceland [PDF]

, 2012
Glacier surfaces have a surprisingly complex ecology. Cryoconite holes contain diverse invertebrate communities while other invertebrates, such as Collembola often graze on algae and windblown dead organic on the glacier surface.
A Babenko, A Fjellberg, A Fjellberg, A Fjellberg, A Fjellberg, AJ Hodson, AM Anesio, C Säwström, CJ Heusser, D Scherrer, DE Walter, DJ Graham, DL Porazinska, FL Perez, GW Krantz, H Dastych, H Kopeszki, HT Shacklette, ID Hodkinson, IS Jonsdottir, J Eythórsson, M Chenet, M Makkonen, N. G. Midgley, P Gjelstrup, PJA Pugh, PL Hartzell, PL Hartzell, PR Porter, RA Wharton, S. J. Coulson, SJ Coulson, SJ Coulson, SP Hopkin, T Birkemoe, T Birkemoe, TC Hawes, TRE Southwood, W Block, WH Smet De, WH Smet De   +40 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Impact of Plasma Membrane Domains on IgG Fc Receptor Function

Frontiers in Immunology, 2020
Lipid cell membranes not only represent the physical boundaries of cells. They also actively participate in many cellular processes. This contribution is facilitated by highly complex mixtures of different lipids and incorporation of various membrane ...
Sibel Kara, Lukas Amon, Jennifer J. Lühr, Jennifer J. Lühr, Falk Nimmerjahn, Falk Nimmerjahn, Falk Nimmerjahn, Diana Dudziak, Diana Dudziak, Diana Dudziak, Diana Dudziak, Anja Lux, Anja Lux   +12 more
doaj   +1 more source

Interactions between vaccinia virus and sensitized macrophages in vitro [PDF]

, 1975
The action of peritoneal exudate cells (PEC) from normal and vaccinia virus infected mice on infectious vaccinia virus particles was investigatedin vitro. PEC from immune mice showed a significantly higher infectivity titre reduction (virus clearance, VC)
A. V. Boand, B. Rager-Zismann, B. Vernon-Roberts, C. A. Mims, C. A. Mims, D. R. Ginder, F. B. Bang, F. R. Avila, G. B. Mackaness, J. A. Roberts, J. G. Stevens, K. T. Brunner, L. F. Reed, M. Nishmi, M. Rabinowitch, M. Rabinowitch, M. S. Hirsch, R. Benda, R. Evans, R. Gallily, R. J. North, R. M. Schultz, R. T. Johnson, S. Ueda, W. A. F. Tompkins, W. Dabrowski   +25 more
core   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source