Results 51 to 60 of about 3,056 (209)

Hydrophilic Monomethyl Auristatin E Derivatives as Novel Candidates for the Design of Antibody-Drug Conjugates

Separations, 2018
Antibody-drug conjugates (ADCs) are promising state-of-the-art biopharmaceutical drugs for selective drug-delivery applications and the treatment of diseases such as cancer.
Filip S. Ekholm, Suvi-Katriina Ruokonen, Marina Redón, Virve Pitkänen, Anja Vilkman, Juhani Saarinen, Jari Helin, Tero Satomaa, Susanne K. Wiedmer   +8 more
doaj   +1 more source

Capillary‐Based Physicochemical Characterization of Lipid Nanoparticles

ELECTROPHORESIS, Volume 46, Issue 21, Page 1588-1599, November 2025.
ABSTRACT Lipid nanoparticles (LNPs) are widely used for the delivery of nucleic acid (NAs), most notably in gene therapy and messenger ribonucleic acid (mRNA)‐based vaccines. Understanding their physicochemical properties is essential, yet current analytical approaches often fall short in capturing their complexity.
Evrim Ümit Kuzucu, Valentin Schittny, Jörg Huwyler, Maria Anna Schwarz   +3 more
wiley   +1 more source

Miniaturization in action: High-resolution, low-cost analytical platforms for biomedical and pharmaceutical research

Journal of Pharmaceutical and Biomedical Analysis Open
Growing concerns over environmental pollution have led to increased emphasis on Green Chemistry and, more specifically, Green Analytical Chemistry (GAC).
Erika Maria Ricci, Miryam Perrucci, Marcello Locatelli, Imran Ali, Halil I. Ulusoy, Abuzar Kabir, Fotouh R. Mansour   +6 more
doaj   +1 more source

Separation of Xylidine Isomers by Micellar Electrokinetic Chromatography [PDF]

Journal of Chromatographic Science, 2001
Xylidines are important precursors for the production of dyes, drugs, and various other products. Because of the high carcinogenic nature of some xylidine isomers it becomes very essential and relevant to develop suitable analytical procedures to separate isomers as well as enhance detection at very low concentrations.
R. Jeevan, G. Jeevan, R. Chandrasekar, M. Bhaskar, G. Radhakrishnan   +4 more
openaire   +2 more sources

Catalpol: An Iridoid Glycoside With Potential in Combating Cancer Development and Progression—A Comprehensive Review

Phytotherapy Research, Volume 39, Issue 10, Page 4950-4971, October 2025.
Catalpol's potential in inhibiting cancer development and progression through various pathways. ABSTRACT Catalpol, a natural iridoid glycoside known for its anti‐proliferative effects, has been proposed as an anticancer compound. Catalpol targets critical processes involved in cancer cell progression, like malignant proliferation, apoptosis, and ...
Lucas Fornari Laurindo, Victória Dogani Rodrigues, Elen Landgraf Guiguer, Lívia Fornari Laurindo, Debora Aparecida Pires de Campos Zuccari, Claudia Rucco Penteado Detregiachi, Adriano Cressoni Araújo, Jéssica da Silva Camarinha Oliveira, Durvanei Augusto Maria, Jefferson Aparecido Dias, Rose Eli Grassi Rici, Caroline Barbalho Lamas, Rosa Direito, Sandra Maria Barbalho   +13 more
wiley   +1 more source

Determination of urinary hippuric acid by micellar electrokinetic capillary chromatography

, 2003
We propose a method for the simultaneous determination of hippuric acid (HA) and creatinine based on capillary micellar electrokinetic chromatography.
VINCENZONI F, ROSSETTI DV, VITALI A, ZUPPI C, CASTAGNOLA M, MESSANA, IRENE, GIARDINA B   +6 more
core   +1 more source

3D Nanoflowers of Binary Metal‐Selenide for Improved Electrochemical Sensing and High‐Energy‐Density Energy Storage

Small, Volume 21, Issue 37, September 18, 2025.
This study reports the hydrothermal synthesis of 3D NiVSe nanoflowers from NiSe nanoflakes and VSe nanobelts at 180 °C for 12 h. The hybrid structure enables dual functionality: ultrasensitive electrochemical detection of nilutamide with a detection limit of 0.2 nm, and high‐performance supercapacitor behavior with an energy density of 85 Wh kg⁻¹ at a ...
Keerthika Devi Ramadhass, Chun Che Lin
wiley   +1 more source

Micellar and microemulsion electrokinetic chromatography of hop bitter acids.

, 1996
The elution order of the hop alpha- and beta-acids has been studied under different modes of electrokinetic separation. A model is advanced to explain the shorter migration times of the more hydrophobic beta-acids compared to the alpha-acids in micellar ...
Roman Szücs, Erik Van Hove, Szucs, Roman, Sandra, Patrick, Van Hove, Erik, Pat Sandra   +5 more
core   +1 more source

FUNDAMENTOS DE ELETROFORESE CAPILAR: UMA ABORDAGEM POR ANIMAÇÕES

Química Nova, 2015
Among the analytical separation techniques, capillary electrophoresis (CE) has attracted attention in both academic and industrial fields, mainly owing to its efficiency, short analysis times, low reagent consumption and residue generation.
Fernando Antonio Simas Vaz, Cledson Lopes Marta de Oliveira, Marcone Augusto Leal de Oliveira   +2 more
doaj   +1 more source

Efficient and Symmetric Temperature Control in Capillary Electrophoresis II: Thermal Performance When Cooling Capillaries Are Tied Around Analytical Capillaries

Journal of Separation Science, Volume 48, Issue 8, August 2025.
ABSTRACT Current commercially available capillary electrophoresis instruments lack centrosymmetric and efficient temperature control along the whole extend of the capillary. Here we studied the characteristics and thermal performance of a cooling system that consists of cooling capillaries (fused silica microtubes) which are tied around the complete ...
Leonel Bortolotto Macedo, Cristian Bonatto, Tarso B. Ledur Kist   +2 more
wiley   +1 more source