Results 61 to 70 of about 1,107 (169)
Journal of Separation Science, Volume 48, Issue 8, August 2025.ABSTRACT Current commercially available capillary electrophoresis instruments lack centrosymmetric and efficient temperature control along the whole extend of the capillary. Here we studied the characteristics and thermal performance of a cooling system that consists of cooling capillaries (fused silica microtubes) which are tied around the complete ...
Leonel Bortolotto Macedo +2 more
wiley +1 more source
Separation of Xylidine Isomers by Micellar Electrokinetic Chromatography [PDF]
Journal of Chromatographic Science, 2001 Xylidines are important precursors for the production of dyes, drugs, and various other products. Because of the high carcinogenic nature of some xylidine isomers it becomes very essential and relevant to develop suitable analytical procedures to separate isomers as well as enhance detection at very low concentrations.
R. Jeevan +4 more
openaire +2 more sources
British Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 1899-1913, July 2025.Aims To identify, evaluate and summarize all published literature that investigated manipulations to pharmaceutical dosage forms of psychotropic medications that could be used for the purposes of tapering. Methods A systematic literature review was carried out of the available published literature on manipulations performed to psychotropic medications ...
Denis O'Brien +3 more
wiley +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2017 A rapid and sensitive micellar electrokinetic capillary chromatography method with UV photodiode-array detection was developed for the simultaneous determination of atorvastatin and ezetimibe in fixed dose drug combination.
Blanka Székely-Szentmiklósi +4 more
doaj +1 more source
ELECTROPHORESIS, Volume 46, Issue 13-14, Page 933-953, July 2025.ABSTRACT The ICH Q14 guideline introduces a structured framework for analytical method development based on Analytical Quality by Design (AQbD) principles, aiming to ensure robust, reliable, and fit‐for‐purpose methods throughout the product lifecycle.
Ewoud van Tricht +1 more
wiley +1 more source
ELECTROPHORESIS, Volume 46, Issue 11-12, Page 653-668, June 2025.ABSTRACT Capillary electrophoresis (CE) often offers superior separation relative to chromatography for macromolecules like monoclonal antibodies (mAbs), a major pharmaceutical class. However, electropherogram baselines pose challenges that traditional chromatography algorithms cannot address, requiring complex integration processes.
Timothy Blanc +2 more
wiley +1 more source
Gradient micellar electrokinetic chromatography.
SEIBUTSU BUTSURI KAGAKU, 2008 A Surfactant gradient method was developed for miceller electrokinetic chromatography (MEKC). In the present method, electroosmotic flow was suppressed almost completely and thus, micelles in a running solution of the inlet vial were introduced in turn into the capillary during operations.
Esaka, Yukihiro, Uno, Bunji
openaire +2 more sources
Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley +1 more source
SeparationsThe unregulated consumption of corticosteroids causes significant adverse effects on human health. Therefore, it is important to develop methodologies that allow their analysis in pharmaceutical matrices with competitive analysis times and costs.
Karen A. Escamilla-Lara +3 more
doaj +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2014 The applicability of capillary electrophoresis for the analysis of four extensively used penicillin derivatives (benzylpenicillin, ampicillin, amoxicillin, oxacilllin) has been studied.
Brigitta Simon +2 more
doaj +1 more source