Results 61 to 70 of about 3,056 (209)

ION-EXCHANGE ELECTROKINETIC CAPILLARY CHROMATOGRAPHY WITH STARBURST(PAMAM) DENDRIMERS - A ROUTE TOWARDS HIGH-PERFORMANCE ELECTROKINETIC CAPILLARY CHROMATOGRAPHY

open access: yes, 1995
The use of different generations of Starburst (pamam) dendrimers provides a new opportunity for ion-exchange electrokinetic capillary chromatography. The uniform surface charge density and the structural homogeneity of these macroelectrolytes provide ...
Patamia, Maria   +13 more
core   +1 more source

A systematic review of manipulations to pharmaceutical dosage forms used in psychotropic tapering plans

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 1899-1913, July 2025.
Aims To identify, evaluate and summarize all published literature that investigated manipulations to pharmaceutical dosage forms of psychotropic medications that could be used for the purposes of tapering. Methods A systematic literature review was carried out of the available published literature on manipulations performed to psychotropic medications ...
Denis O'Brien   +3 more
wiley   +1 more source

OPTIMIZATION OF PHENYLTHIOHYDANTOINAMINO ACID SEPARATION BY MICELLAR ELECTROKINETIC CAPILLARY CHROMATOGRAPHY

open access: yes, 1993
Optimization of phenylthiohydantion (PTH)-amino acid separation by micellar electrokinetic capillary chromatography was achieved by the use of a weighted variable-size simplex algorithm.
Giardina, Bruno   +4 more
core   +1 more source

Simultaneous determination of atorvastatin and ezetimibe from combined pharmaceutical products by micellar electrokinetic capillary chromatography

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2017
A rapid and sensitive micellar electrokinetic capillary chromatography method with UV photodiode-array detection was developed for the simultaneous determination of atorvastatin and ezetimibe in fixed dose drug combination.
Blanka Székely-Szentmiklósi   +4 more
doaj   +1 more source

A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

open access: yesELECTROPHORESIS, Volume 46, Issue 13-14, Page 933-953, July 2025.
ABSTRACT The ICH Q14 guideline introduces a structured framework for analytical method development based on Analytical Quality by Design (AQbD) principles, aiming to ensure robust, reliable, and fit‐for‐purpose methods throughout the product lifecycle.
Ewoud van Tricht   +1 more
wiley   +1 more source

Methods development for separation of fungicides using micellar electrokinetic chromatography [PDF]

open access: yes, 2006
In this study, micellar electrokinetic chromatography (MEKC) was used for the simultaneous separation of three different classes of fungicides. Separations were done at 210 nm with on-column UV detection.
A'ubid, Na'emah
core  

Fundamentals of micellar electrokinetic chromatography (MEKC) [PDF]

open access: yes, 2011
Micellar electrokinetic chromatography (MEKC) is a useful branch of capillary electrophoresis (CE) that utilizes surfactant above critical micelle concentration (CMC) as pseudo-stationary phase.
Duc Phuc Do   +5 more
core   +1 more source

Peak Integration of Electropherograms in GMP and Research Labs: Navigating Increased Scrutiny Amid Data Integrity Audits and Inspections

open access: yesELECTROPHORESIS, Volume 46, Issue 11-12, Page 653-668, June 2025.
ABSTRACT Capillary electrophoresis (CE) often offers superior separation relative to chromatography for macromolecules like monoclonal antibodies (mAbs), a major pharmaceutical class. However, electropherogram baselines pose challenges that traditional chromatography algorithms cannot address, requiring complex integration processes.
Timothy Blanc   +2 more
wiley   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

open access: yesMass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Multivariate optimization in micellar electrokinetic capillary chromatography

open access: yes, 2000
The optimization of the organic modifier concentration in micellar electrokinetic capillary chromatography (MECC) has been achieved by a uniform design and iterative optimization method, which has been developed for the optimization of composition of the
Zou, HF   +4 more
core  

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