Results 61 to 70 of about 604,617 (209)

Capillary‐Based Physicochemical Characterization of Lipid Nanoparticles

open access: yesELECTROPHORESIS, Volume 46, Issue 21, Page 1588-1599, November 2025.
ABSTRACT Lipid nanoparticles (LNPs) are widely used for the delivery of nucleic acid (NAs), most notably in gene therapy and messenger ribonucleic acid (mRNA)‐based vaccines. Understanding their physicochemical properties is essential, yet current analytical approaches often fall short in capturing their complexity.
Evrim Ümit Kuzucu   +3 more
wiley   +1 more source

Analysis of ketoprofen, methylparaben and propylparaben by micellar electrokinetic chromatography [PDF]

open access: yes, 2007
1. ABSTRACT ANALYSIS OF KETOPROFEN, METHYLPARABEN AND PROPYLPARABEN BY MICELLAR ELECTROKINETIC CHROMATOGRAPHY Josef Balcar Charles University in Prague, Faculty of Pharmacy in Hradec Králové, Department of Analytical Chemistry, Heyrovského 1203, Hradec ...
Balcar, Josef
core  

Catalpol: An Iridoid Glycoside With Potential in Combating Cancer Development and Progression—A Comprehensive Review

open access: yesPhytotherapy Research, Volume 39, Issue 10, Page 4950-4971, October 2025.
Catalpol's potential in inhibiting cancer development and progression through various pathways. ABSTRACT Catalpol, a natural iridoid glycoside known for its anti‐proliferative effects, has been proposed as an anticancer compound. Catalpol targets critical processes involved in cancer cell progression, like malignant proliferation, apoptosis, and ...
Lucas Fornari Laurindo   +13 more
wiley   +1 more source

Separation of Xylidine Isomers by Micellar Electrokinetic Chromatography [PDF]

open access: yesJournal of Chromatographic Science, 2001
Xylidines are important precursors for the production of dyes, drugs, and various other products. Because of the high carcinogenic nature of some xylidine isomers it becomes very essential and relevant to develop suitable analytical procedures to separate isomers as well as enhance detection at very low concentrations.
R. Jeevan   +4 more
openaire   +2 more sources

3D Nanoflowers of Binary Metal‐Selenide for Improved Electrochemical Sensing and High‐Energy‐Density Energy Storage

open access: yesSmall, Volume 21, Issue 37, September 18, 2025.
This study reports the hydrothermal synthesis of 3D NiVSe nanoflowers from NiSe nanoflakes and VSe nanobelts at 180 °C for 12 h. The hybrid structure enables dual functionality: ultrasensitive electrochemical detection of nilutamide with a detection limit of 0.2 nm, and high‐performance supercapacitor behavior with an energy density of 85 Wh kg⁻¹ at a ...
Keerthika Devi Ramadhass, Chun Che Lin
wiley   +1 more source

Analysis of Lignans Using Micellar Electrokinetic Chromatography

open access: yes, 2009
Micellar electrokinetic chromatography (MEKC) was used to separate twelve lignan compounds originating from Phyllanthus plants. To increase the reliability of peak identification, two micellar systems, the sodium dodecyl sulfate (SDS) and sodium ...
郭錦樺;李水盛;孫紹文   +1 more
core   +1 more source

Simultaneous determination of atorvastatin and ezetimibe from combined pharmaceutical products by micellar electrokinetic capillary chromatography

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2017
A rapid and sensitive micellar electrokinetic capillary chromatography method with UV photodiode-array detection was developed for the simultaneous determination of atorvastatin and ezetimibe in fixed dose drug combination.
Blanka Székely-Szentmiklósi   +4 more
doaj   +1 more source

Efficient and Symmetric Temperature Control in Capillary Electrophoresis II: Thermal Performance When Cooling Capillaries Are Tied Around Analytical Capillaries

open access: yesJournal of Separation Science, Volume 48, Issue 8, August 2025.
ABSTRACT Current commercially available capillary electrophoresis instruments lack centrosymmetric and efficient temperature control along the whole extend of the capillary. Here we studied the characteristics and thermal performance of a cooling system that consists of cooling capillaries (fused silica microtubes) which are tied around the complete ...
Leonel Bortolotto Macedo   +2 more
wiley   +1 more source

A systematic review of manipulations to pharmaceutical dosage forms used in psychotropic tapering plans

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 7, Page 1899-1913, July 2025.
Aims To identify, evaluate and summarize all published literature that investigated manipulations to pharmaceutical dosage forms of psychotropic medications that could be used for the purposes of tapering. Methods A systematic literature review was carried out of the available published literature on manipulations performed to psychotropic medications ...
Denis O'Brien   +3 more
wiley   +1 more source

A Practical Approach to Implementing ICH Q14: Tools for Analytical Quality by Design in Capillary Electrophoresis Method Development

open access: yesELECTROPHORESIS, Volume 46, Issue 13-14, Page 933-953, July 2025.
ABSTRACT The ICH Q14 guideline introduces a structured framework for analytical method development based on Analytical Quality by Design (AQbD) principles, aiming to ensure robust, reliable, and fit‐for‐purpose methods throughout the product lifecycle.
Ewoud van Tricht   +1 more
wiley   +1 more source

Home - About - Disclaimer - Privacy