Results 101 to 110 of about 14,460 (241)

Confined spaces in space: Cerebral implications of chronic elevations of inspired carbon dioxide and implications for long‐duration space travel

open access: yesExperimental Physiology, EarlyView.
Abstract Cerebrovascular regulation is critically dependent upon the arterial partial pressure of carbon dioxide (PaCO2${P_{{\mathrm{aC}}{{\mathrm{O}}_{\mathrm{2}}}}}$), owing to its effect on cerebral blood flow, tissue PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_{\mathrm{2}}}}}$, tissue proton concentration, cerebral metabolism and cognitive and neuronal ...
Jay M. J. R. Carr   +2 more
wiley   +1 more source

Blood flow restriction: The acute effects of body tilting and reduced gravity analogues on limb occlusion pressure

open access: yesExperimental Physiology, EarlyView.
Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley   +1 more source

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

open access: yesExperimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris   +10 more
wiley   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

open access: yesExperimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Vascular, inflammatory and perceptual responses to hot water immersion: Impacts of water depth and temperature in young healthy adults

open access: yesExperimental Physiology, EarlyView.
Abstract Repeated hot water immersion can improve cardiovascular health; however, the respective effects of distinct immersion protocols remain unclear. Twenty‐two healthy adults completed three 30‐min hot water immersion bouts of different water temperatures and immersion depths (40°C shoulder‐deep immersion, 40‐Shoulder; 42°C waist‐deep immersion, 42‐
Campbell Menzies   +5 more
wiley   +1 more source

Blood flow restriction exercise during microgravity exposure in parabolic flight

open access: yesExperimental Physiology, EarlyView.
Abstract This case report evaluates whether it is possible to perform blood flow restriction (BFR) exercise during exposure to microgravity. The objectives were three‐fold: (1) to determine if a personalised tourniquet system (PTS) hardware technology performs nominally and enables BFR exercise in microgravity; (2) to determine if BFR augments the ...
Yannick Laflamme   +2 more
wiley   +1 more source

Sex differences in the prefrontal cortex and muscle oxygenation during exercise until exhaustion in endurance‐trained individuals

open access: yesExperimental Physiology, EarlyView.
Abstract figure legend During cardiopulmonary exercise testing, the decline in oxygenation in the prefrontal cortex of women is striking. This crucial brain area is directly involved in planning motor tasks. The decline is particularly pronounced at higher exercise intensities, especially after reaching the respiratory compensation point or anaerobic ...
Daniel Ramos‐López   +12 more
wiley   +1 more source

Quantifying microvascular responses to local heating using optical coherence tomography: Comparison between skin sites and sex differences

open access: yesExperimental Physiology, EarlyView.
Summary of the study design, metholodgy, results and conclusions. Abstract Due to a lack of technical capacity to directly visualise and quantify microvessels in the skin, little is known regarding regional and/or sex differences. We compared diameter, velocity, flow and density at four regional sites using a novel optical coherence tomography (OCT ...
Juliene G. Costa   +5 more
wiley   +1 more source

Vascular and skeletal muscle oxidative capacity responses to continuous double and single leg cycling

open access: yesExperimental Physiology, EarlyView.
Abstract The purpose of this work was to determine endothelial, microvascular, skeletal muscle oxidative capacity (SMOC) and cardiorespiratory responses to an acute bout of continuous single leg cycling (SLC) and double leg cycling (DLC). Ten recreationally active men and women volunteered to participate in this investigation and reported to the ...
Edward Z. Pelka   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy