Results 51 to 60 of about 145,554 (258)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Relationship between low mood and micro-expression processing: evidence of negative bias in interpreting fleeting facial expressions

Royal Society Open Science
Depression affects the recognition of emotion in facial expressions by reducing the detection accuracy and adding a bias towards negativity. However, no study has examined associations between depression and the recognition of microfacial expressions ...
Kasia Wezowski, Ian S. Penton-Voak
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Objective Classes for Micro-Facial Expression Recognition

Journal of Imaging, 2018
Micro-expressions are brief spontaneous facial expressions that appear on a face when a person conceals an emotion, making them different to normal facial expressions in subtlety and duration.
Adrian K. Davison, Walied Merghani, Moi Hoon Yap   +2 more
doaj   +1 more source

LEARNet: Dynamic Imaging Network for Micro Expression Recognition [PDF]

IEEE Transactions on Image Processing, 2020
Unlike prevalent facial expressions, micro expressions have subtle, involuntary muscle movements which are short-lived in nature. These minute muscle movements reflect true emotions of a person. Due to the short duration and low intensity, these micro-expressions are very difficult to perceive and interpret correctly.
Monu Verma, Santosh Kumar Vipparthi, Girdhari Singh, Subrahmanyam Murala   +3 more
openaire   +3 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Haphazard Cuboids Feature Extraction for Micro-Expression Recognition

IEEE Access, 2022
Facial micro-expressions can reveal a person’s actual mental state and emotions. Therefore, it has crucial applications in many fields, such as lie detection, clinical medicine, and defense security.
Gang Wang, Shucheng Huang, Zizhao Dong
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

PRNet: A Priori Embedded Network for Real-World Blind Micro-Expression Recognition

Mathematics
Micro-expressions, fleeting and often unnoticed facial cues, hold the key to uncovering concealed emotions, offering significant implications for understanding emotions, cognition, and psychological processes.
Xin Liu, Fugang Wang, Hui Zeng, Yile Chen, Liang Zheng, Junming Chen   +5 more
doaj   +1 more source