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Micro-RNA: The darkhorse of cancer

Cellular Signalling, 2021
The discovery of micro RNAs (miRNA) in cancer has opened up new vistas for researchers in recent years. Micro RNAs area set of small, endogenous, highly conserved, non-coding RNAs that control the expression of about 30% genes at post-transcriptional levels.
Mridul, Budakoti   +7 more
openaire   +2 more sources

Fecal (micro) RNA Isolation

Journal of Visualized Experiments, 2020
It is becoming clear that RNA exists in the gut lumen and feces in animals and humans. The protocol described below isolates total RNA including microRNAs from fecal samples of animal and human subjects. The aim is to isolate total RNA with high purity and quantity for downstream analyses such as RNA sequencing, RT-PCR, and micro-array.
Fyonn H, Dhang   +2 more
openaire   +2 more sources

A Homogenous Assay for Micro RNA Maturation

Angewandte Chemie - International Edition, 2006
Christoph Arenz
exaly   +3 more sources

Identification of micro-RNAs in cotton

Plant Physiology and Biochemistry, 2008
The plant genome has conserved small non-coding microRNAs (miRNAs) genes about 20-24 nucleotides long. They play a vital role in the gene regulation at various stages of plant life. Their conserved nature among the various organisms not only suggests their early evolution in eukaryotes but also makes them a good source of new miRNA discovery by ...
Muhammad Younas, Khan Barozai   +9 more
openaire   +2 more sources

Micro-RNAs in transplant tolerance

Current Opinion in Organ Transplantation, 2018
Micro-RNAs (miRNAs) are highly conserved small RNA molecules that have selective gene-regulatory functions. This posttranscriptional regulation by miRNAs is critical for many immunological processes. Many developments in establishing the biological role of miRNAs in solid organ transplantation have been generated in the last decade.
James T, Harden, Sheri M, Krams
openaire   +2 more sources

Revealing micro-RNAs in plants

Trends in Plant Science, 2002
Recent work has resulted in the identification of >100 endogenous non-coding small RNA molecules in plants. These micro-RNAs (miRNAs) have the capacity to regulate a range of predicted target mRNAs, many of which are transcription factors involved in the control of meristem identity. Mutants defective in either CARPEL FACTORY or Hen1 fail to accumulate
openaire   +2 more sources

Circulating Micro-RNAs in Patients with Hypophosphatasia Results of the first micro-RNA analysis in HPP

The Journal of Clinical Endocrinology & Metabolism
Abstract Introduction Adult hypophosphatasia (HPP) patients present with diffuse heterogenous symptoms often mimicking rheumatological diseases or osteoporosis and therefore accompanied by delayed diagnosis.
Judith Haschka   +11 more
openaire   +2 more sources

Micro RNA Profiling

2007
MicroRNAs (miRNAs) are small regulatory RNAs varying in length between 20 and 24 nucleotides. They are thought to play a key role during development by negative gene regulation at the post-transcriptional level. Recent studies using quantitative polymerase chain reaction (QPCR) and northern blot analysis have reported the presence of several miRNA ...
Uma Lakshmipathy   +4 more
openaire   +1 more source

[Micro-RNA and oncogenesis].

Bulletin du cancer, 2005
MicroRNA are endogenous molecules which negatively regulate the expression of a variety of genes. These tiny non coding RNA molecules--18 to 25 nucleotides in length--repress, with efficiency and specificity- translation of target mRNA into protein, according to a process akin to RNA interference.
Jean, Bénard, Setha, Douc-Rasy
openaire   +1 more source

Micro-RNA Implications in Type-1 Diabetes Mellitus: A Review of Literature

International Journal of Molecular Sciences, 2021
Vasiliki-Rengina Tsinopoulou   +2 more
exaly  

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