Results 81 to 90 of about 1,267,069 (198)
ABSTRACT Background The role of histone lactylation in diabetes associated renal fibrosis remains poorly defined. In this study, we investigated the contribution of histone H4 lysine 12 lactylation (H4K12la) to abnormal glycolysis and renal fibrogenesis in diabetic kidney disease (DKD) and evaluated sodium butyrate (NaB) as a potential therapeutic ...
Ping He +10 more
wiley +1 more source
Transcriptional risk score for chronic kidney disease: relation to Alzheimer's disease
Abstract INTRODUCTION Although Alzheimer's disease (AD) is prevalent in individuals with chronic kidney disease (CKD), the mechanistic link remains unclear. We assessed the impact of CKD transcriptional risk on AD endophenotypes. METHODS We calculated the CKD transcriptional risk score (CKD‐TRS) using blood transcriptomes from the Alzheimer's Disease ...
Jung‐Min Pyun +6 more
wiley +1 more source
Sleep Duration and Diabetic Kidney Disease
Aims: Abnormally short or long durations of sleep have been proposed as a risk factors for diabetes and its micro- and macro-vascular complications. However, the relationship between sleep duration and diabetic kidney disease (DKD) has not been well ...
Nicholas Y. Q. Tan +10 more
doaj +1 more source
NSUN4‐mediated upregulation of SMURF1 promoted mitochondrial fission and inhibited mitochondrial fusion to accelerate DN progression via increasing CAMK1 ubiquitination. Abstract Background NOP2/Sun RNA methyltransferase family member 4 (NSUN4)‐mediated 5‐methylcytosine (m5C) modification has been implicated in diabetes‐related diseases.
Danyi Yang +5 more
wiley +1 more source
Effect of serum cystatin C in early diabetic nephropathy in type 2 Iraqi diabetic patients
Objective This study aimed to find the effect of serum Cystatin C in early diabetic nephropathy. Method This study was conducted in Al Kindy Teaching Hospital during the period from December, 2015 to June, 2016.
Ahmed Abed Kadhem Al-Saedy +2 more
doaj
SIGNIFICANCE OF MICRO ALBUMINURIA AS A PREDICTIVE FACTOR IN ACUTE MYOCARDIAL INFECTION
OBJECTIVES: A study was undertaken among 50 non-diabetic patients of acute myocardial infarction (AMI) admitted within 24hours of the onset of pain for investigation of the prevalence and significance of microalbuminuria (MA) as a predictor of in-hospital mortality and also to correlate it with other well-established prognostic markers.
Vijay Kumar B A +4 more
openaire +1 more source
The comparative pharmacology and cardiometabolic outcomes of semaglutide, liraglutide and tirzepatide, integrating evidence from major clinical trial programs and meta‐analyses. ABSTRACT Background Cardiometabolic disorders such as type 2 diabetes mellitus (T2DM), obesity and cardiovascular disease (CVD) remain major global health challenges.
Hiba Bawadi +4 more
wiley +1 more source
Background Indigenous peoples worldwide are experiencing elevated rates of type 2 diabetes and its complications. To better understand the disproportionate burden of diabetic end stage renal disease (ESRD) among Canadian First Nations people (FN), we ...
Dyck Roland F +2 more
doaj +1 more source
ABSTRACT Background and Aim Over 200 million people in developing and industrialized countries are exposed to arsenic poisoning. Fine particulate matter (PM2.5) constitutes a significant air contaminant, especially in urban and industrial suburbs.
Nafisa Akua Assan +10 more
wiley +1 more source
A review of micro albuminuria and its concmitants.
Aim: To collate information on the aetiology, concomitants, pathogenesis and management of micro albuminuria to guide in patient management. Methods: An English language literature search using medline (1991-2000) was done to access research/review articles on micro albuminuria.
openaire +2 more sources

