Results 81 to 90 of about 1,267,069 (198)

Sodium Butyrate Attenuates Renal Fibrosis by Regulating Glycolysis and Histone H4K12 Lactylation in Diabetic Kidney Disease

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9518-9534, October 2026.
ABSTRACT Background The role of histone lactylation in diabetes associated renal fibrosis remains poorly defined. In this study, we investigated the contribution of histone H4 lysine 12 lactylation (H4K12la) to abnormal glycolysis and renal fibrogenesis in diabetic kidney disease (DKD) and evaluated sodium butyrate (NaB) as a potential therapeutic ...
Ping He   +10 more
wiley   +1 more source

Transcriptional risk score for chronic kidney disease: relation to Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Although Alzheimer's disease (AD) is prevalent in individuals with chronic kidney disease (CKD), the mechanistic link remains unclear. We assessed the impact of CKD transcriptional risk on AD endophenotypes. METHODS We calculated the CKD transcriptional risk score (CKD‐TRS) using blood transcriptomes from the Alzheimer's Disease ...
Jung‐Min Pyun   +6 more
wiley   +1 more source

Sleep Duration and Diabetic Kidney Disease

open access: yesFrontiers in Endocrinology, 2019
Aims: Abnormally short or long durations of sleep have been proposed as a risk factors for diabetes and its micro- and macro-vascular complications. However, the relationship between sleep duration and diabetic kidney disease (DKD) has not been well ...
Nicholas Y. Q. Tan   +10 more
doaj   +1 more source

NSUN4‐dependent m5C modification facilitates mitochondrial fission to accelerate diabetic nephropathy process via regulating SMURF1/CAMK1 axis

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
NSUN4‐mediated upregulation of SMURF1 promoted mitochondrial fission and inhibited mitochondrial fusion to accelerate DN progression via increasing CAMK1 ubiquitination. Abstract Background NOP2/Sun RNA methyltransferase family member 4 (NSUN4)‐mediated 5‐methylcytosine (m5C) modification has been implicated in diabetes‐related diseases.
Danyi Yang   +5 more
wiley   +1 more source

Effect of serum cystatin C in early diabetic nephropathy in type 2 Iraqi diabetic patients

open access: yesJournal of Contemporary Medical Sciences, 2017
Objective This study aimed to find the effect of serum Cystatin C in early diabetic nephropathy. Method This study was conducted in Al Kindy Teaching Hospital during the period from December, 2015 to June, 2016.
Ahmed Abed Kadhem Al-Saedy   +2 more
doaj  

SIGNIFICANCE OF MICRO ALBUMINURIA AS A PREDICTIVE FACTOR IN ACUTE MYOCARDIAL INFECTION

open access: yesJournal of Evolution of Medical and Dental Sciences, 2014
OBJECTIVES: A study was undertaken among 50 non-diabetic patients of acute myocardial infarction (AMI) admitted within 24hours of the onset of pain for investigation of the prevalence and significance of microalbuminuria (MA) as a predictor of in-hospital mortality and also to correlate it with other well-established prognostic markers.
Vijay Kumar B A   +4 more
openaire   +1 more source

Impact of Semaglutide, Liraglutide and Tirzepatide on Cardiometabolic Outcomes: A Comparative Narrative Review

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
The comparative pharmacology and cardiometabolic outcomes of semaglutide, liraglutide and tirzepatide, integrating evidence from major clinical trial programs and meta‐analyses. ABSTRACT Background Cardiometabolic disorders such as type 2 diabetes mellitus (T2DM), obesity and cardiovascular disease (CVD) remain major global health challenges.
Hiba Bawadi   +4 more
wiley   +1 more source

Prevalence, determinants and co-morbidities of chronic kidney disease among First Nations adults with diabetes: results from the CIRCLE study

open access: yesBMC Nephrology, 2012
Background Indigenous peoples worldwide are experiencing elevated rates of type 2 diabetes and its complications. To better understand the disproportionate burden of diabetic end stage renal disease (ESRD) among Canadian First Nations people (FN), we ...
Dyck Roland F   +2 more
doaj   +1 more source

Evaluation of Ambient Air Particulate Matter, Urine Arsenic Levels and the Effect on Residents Health in an Artisanal Mining Community and an Incorporated Mining Community in Ghana From April 2024 to July 2024: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aim Over 200 million people in developing and industrialized countries are exposed to arsenic poisoning. Fine particulate matter (PM2.5) constitutes a significant air contaminant, especially in urban and industrial suburbs.
Nafisa Akua Assan   +10 more
wiley   +1 more source

A review of micro albuminuria and its concmitants.

open access: yesInternational Journal of Medicine and Health Development, 2002
Aim: To collate information on the aetiology, concomitants, pathogenesis and management of micro albuminuria to guide in patient management. Methods: An English language literature search using medline (1991-2000) was done to access research/review articles on micro albuminuria.
openaire   +2 more sources

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