Results 31 to 40 of about 2,320,756 (247)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Generation of micro channels in AlMg4.5Mn0.7 sheets using a vibration-assisted micro forming process
MATEC Web of Conferences, 2018 Micro forming can be used for a highly efficient manufacturing of small parts like screws or caps. Because of the small dimensions of the structures, high stresses and forming forces occur, especially in the case of micro bulk forming.
Müller Benedikt, Schubert Andreas
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
A new micro scale FE model of crystalline materials in micro forming process
MATEC Web of Conferences, 2016 Micro forming of metals has drawn global attention due to the increasing requirement of micro metal products. However, the size effects become significant in micro forming processes and affect the application of finite element (FE) simulation of micro ...
Luo Liang +5 more
doaj +1 more source
Investigation of advanced strain-path dependent material models for sheet metal forming simulations [PDF]
, 2006 Sheet metal forming processes often involve complex loading sequences. To improve the prediction of some undesirable phenomena, such as springback, physical behavior models should be considered.
BALAN, Tudor +5 more
core +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
EngIn the manufacturing of micro-scale components, geometric dimensional accuracy and product quality are critical factors that directly influence both production costs and efficiency.
Thu Nguyen Thi +2 more
doaj +1 more source
MATEC Web of Conferences, 2018 There is an increased demand for miniature/micro products (such as MEMS) and nanotechnology-based products (such as nano-materials). Micro-manufacturing is a link between Macro-and Nano Manufacturing and an effective means for transferring nanotechnology-
Hijji Hasan +4 more
doaj +1 more source
, 2020 This study investigates the effect of grain size and composition on the material properties and forming limits of commercially supplied stainless steel foil for bipolar plate manufacture via tensile, stretch forming and micro-stamping trials. It is shown
Michael P. Pereira +5 more
core +1 more source
Stochastic simulation of woven composites forming [PDF]
, 1995 A stochastic forming simulation procedure is developed and implemented to investigate the effect of geometric variability in pre-impregnated woven textiles on manufacturing. Image analysis is used to characterise variability in tow directions and unit
Waal, de, H. +7 more
core +1 more source